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How Artificial Intelligence is Transforming Clinical Trial Recruitment

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Navigating Transformative Forces in HealthcareHow Big Data Will Unlock the Potential of HealthcareHow Tech is Changing How Healthcare Must Communicate With PatientsThe Amazonification of HealthcareHow Artificial Intelligence is Transforming Clinical Trial RecruitmentEHR as a GPS for HealthcareMillennial Doctors Transforming Medicine

How Artificial Intelligence is Transforming Clinical Trial Recruitment

How AI is Transforming Clinical Trial Recruitment

The medical world is shifting underneath our feet.

To keep up with the rising demands of empowered patients, physicians and pharma businesses regularly test innovative treatments and medicines during rigorous clinical trials.

But one misguided move can trigger a domino effect, such as when the wrong patients are selected for a clinical trial.

Today’s infographic comes to us from Publicis Health, and it highlights why the current model of clinical trial recruitment urgently needs to change.

The Cost of Clinical Trials

Clinical trials help to determine if a new treatment, drug, or device is safe for the larger patient population.

Patients are at the heart of these clinical trials, and poor patient recruitment has dire consequences:

  • 50% of sites enroll one or no patients in studies
  • 85% of clinical trials fail to retain enough patients
  • 80% of all clinical trials fail to finish on time

A single trial can cost anywhere from $44 million to $115 million. But here’s the kicker – according to a CenterWatch survey, delays can cost a trial between $600,000 and $8 million per day.

For these reasons, it’s crucial for pharma trial sponsors to find the right fit for clinical trials from the start.

A 360° View

The healthcare industry is moving towards a people-based marketing approach, to discover and engage the right patient one-on-one.

Advanced technology and connected patient data work in tandem with millions of real-time consumer behaviors, creating a rich and accurate profile of the perfect patient match.

The use of artificial intelligence, machine learning, and predictive analytics unearth further insights, weighting those patients with the behavioral tendencies most suited for the trial:

Omni-channel targeting
Actively reaching out to patients, wherever they are.

Predictive analytics
Continually refining media channels and messaging to further patient interest.

Ongoing communications
Nurturing relationships with patients, starting with the initial outreach.

Transforming Value

Applying a people-based approach to patient recruitment has a myriad of benefits, many of which live on long after the original trial’s completion.

 AdvantageValue added
Recruitment- Accurate insight generation
- Real time optimization
- Faster and improved quality
- More efficient
- Increased conversion
- Reduced costs
Engagement- Behavioral-based messaging
- Personalized trial participation experiences
- Precise engagement at scale
- Drives patient adherence and retention during a trial
Long-term benefits of data collected- Develops patient profiles for future trials
- Guides the planning of the patient demographic
- Informs drug launch activities
- Accelerates recruitment and reduces start-up costs
- Speeds up commercialization of new drugs
- Supports disease awareness and educational campaigns

As clinical trials are successfully completed on time – allowing new drugs to reach the market faster than before – patients will benefit from easier access to groundbreaking treatments.

This is part five of a seven part series. Stay tuned by subscribing to Visual Capitalist for free, as we wrap up with the final two transformative forces shaping the future of healthcare.

Navigating Transformative Forces in HealthcareHow Big Data Will Unlock the Potential of HealthcareHow Tech is Changing How Healthcare Must Communicate With PatientsThe Amazonification of HealthcareHow Artificial Intelligence is Transforming Clinical Trial RecruitmentEHR as a GPS for HealthcareMillennial Doctors Transforming Medicine

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The Future of Nanotechnology in Medicine

This infographic highlights some of the most promising nanotechnology breakthroughs in medicine, from ‘smart pills’ to targeted cancer treatment.

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The Future of Nanotechnology in Medicine

Around the world, researchers are increasingly thinking smaller to solve some of the biggest problems in medicine.

Though most biological processes happen at the nano level, it wasn’t until recently that new technological advancements helped in opening up the possibility of nanomedicine to healthcare researchers and professionals.

Today’s infographic, which comes to us from Best Health Degrees, highlights some of the most promising research in nanomedicine.

What is Nanotechnology?

Nanotechnology is the engineering of functional systems at the molecular level. The field combines elements of physics and molecular chemistry with engineering to take advantage of unique properties that occur at nanoscale.

One practical example of this technology is the use of tiny carbon nanotubes to transport drugs to specific cells. Not only do these nanotubes have low toxicity and a stable structure, they’re an ideal container for transporting drugs directly to the desired cells.

Small Systems, Big Applications

While many people will be most familiar with nanotech as the technology powering Iron Man’s suit, real world breakthroughs at the nanoscale will soon be saving lives in healthcare.

Here are a few ways nanotechnology is shaping the future of medical treatment:

1. Smart Pills

While smart pill technology is not a new idea — a “pill cam” was cleared by the FDA in 2001 — researchers are coming up with innovative new applications for the concept.

For example, MIT researchers designed an ingestible sensor pill that can be wirelessly controlled. The pill would be a “closed-loop monitoring and treatment” solution, adjusting the dosage of a particular drug based on data gathered within the body (e.g. gastrointestinal system).

An example of this technology in action is the recent FDA-approved smart pill that records when medication was taken. The product, which is approved for people living with schizophrenia and bipolar disorder, allows patients to track their own medication history through a smartphone, or to authorize physicians and caregivers to access that information online.

2. Beating the Big C

Nearly 40% of humans will be diagnosed with cancer at some point in their lifetime, so any breakthrough in cancer treatment will have a widespread impact on society.

On the key issues with conventional chemotherapy and radiation treatments is that the body’s healthy cells can become collateral damage during the process. For this reason, researchers around the world are working on using nano particles to specifically target cancer cells.

Oncology-related drugs have the highest forecasted worldwide prescription drug sales, and targeting will be a key element in the effectiveness of these powerful new drugs.

3. Diagnostics

Medical implants — such as knee and hip replacements — have improved the lives of millions, but a common problem with these implants is the risk of post-surgery inflammation and infection. In many cases, symptoms from an infection are detected so late that treatment is less effective, or the implant will need to be replaced all together.

Nanoscale sensors embedded directly into the implant or surrounding area could detect infection much sooner. As targeted drug delivery becomes more feasible, it could be possible to administer treatment to an infected area at the first sign of infection.

Examples like this show the true promise of nanotechnology in the field of medicine. Before long, gathering data from within the body and administering treatments in real-time could move from science fiction to the real world.

10,000 years ago, man domesticated plants and animals, now it’s time to domesticate molecules.

– Professor Susan Lindquist

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Visualizing Healthcare Spending by Country

Healthcare spending can be measured as a proportion of GDP, by admin costs, and per capita—and the United States comes in first in every category.

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How Much Do OECD Countries Spend on Healthcare?

When you start feeling ill, the first line of defense is typically to have a doctor assess the symptoms—but how much you end up paying for a visit differs greatly by region.

Today’s interactive visualization was created by HealthDataViz consultant Lindsay Betzendahl, who also founded #ProjectHealthViz. The data considers how healthcare spending by country stacks up across the 36 Organization for Economic Cooperation (OECD) members, and how it has changed since 2010.

One thing is clear—the United States comes in first place in each category, but that’s not necessarily a good thing:

 🇺🇸 United States🌐 OECD Average
Healthcare Spending (% of GDP)16.9% (#1)8.8%
Admin Costs as % of Health Spend8.3% (#1)*~3%
Per Capita Prices (Current PPPs, USD)$10,586 (#1)$3,992

*Although Costa Rica’s figure was higher in 2016, more recent data is not yet available.

Let’s look at each individual cost category, to see what else we can learn.

What Portion of GDP Goes Towards Health?

Population health is a strong determinant in quality of life. As such, how much a country spends on healthcare as a percentage of gross domestic product (GDP) can be an important indicator.

The U.S. spends 16.9% of GDP on its healthcare, nearly double the OECD average of 8.8%. That’s also over 4 percentage points (p.p.) above Switzerland, which ranks second with 12.2% healthcare spending by GDP.

The problem? While Switzerland consistently ranks as having one of the best healthcare systems in the world, the U.S. lags behind—which means that expenditures are not always translating into better health outcomes for patients.

Where’s the Money Going?

Looking after the health of millions of people is a lot of work, and this is where spending on healthcare administration and financing comes into play. Funds are allocated to medical resource providers, who manage everything from health records to salaries and insurance bills.

The U.S. spends about 8.3% of its total healthcare expenditures on these complex costs today, which is a marginal increase from 7.5% in 2010. Interestingly, Costa Rica’s healthcare spending on the same metric was even higher in 2016, at 9.5% of the total.

On the bright side, Mexico has been making strides in the past few years: administrative spending plunged from 10.3% in 2013, down to 4.6% in 2017.

Globally, advancements in health-tech are helping to reduce costs by streamlining tedious processes. However, it’s still not enough—and these immense costs trickle down to patients.

How Much Does Each Person Shell Out?

Over the past eight years, a majority of OECD countries have seen their healthcare spending per capita climb, with Luxembourg and Greece being the only exceptions. The average OECD country’s spend was $3,992 per capita in 2018, up from $3,080 in 2010—nearly a 30% increase.

However, the U.S. experiences the most dramatic sticker shock by far. At $10,586 per head, the U.S. average is already more than double the OECD average. What’s more, this is a 33.3% increase from $7,939 in healthcare spending per capita in 2010.

As the U.S. healthcare reform debate around prices and quality of care rages on, it’s important to remember that healthy people are the backbone of any country’s long-term economic growth.

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