Flying High: The Top Ten Airline Routes by Revenue
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Flying High: The Top Ten Airline Routes by Revenue

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Top airline routes by revenue

Flying High: The Top 10 Airline Routes by Revenue

The airline industry is a tough business. Profit margins are narrow, airplanes are expensive to run and maintain, and government regulation and taxation can be onerous and unpredictable.

In addition, demand can stall by the outbreak of disease, recession, war, or terrorism. So when a company has a winning airline route, it makes all the difference to a company’s bottom line.

Today’s visualization uses data from OAG Aviation Worldwide, which tracked the airline routes that generated the most revenue from April 2018 to March 2019.

Top 10 Highest Revenue Routes by Airline

North American routes dominate the global rankings. However, it is the connections from the U.S Northeast and Europe that generate the most revenue and often the most delays.

Only one route breaks the billion dollar barrier: British Airways’ service between London Heathrow Airport (LHR) and New York’s John F. Kennedy Airport (JFK).

AirlineAirport PairCountriesTotal Revenue US$ 2018/19
British AirwaysJFK-LHR🇺🇸🇬🇧$1,159,126,794
Qantas AirlinesMEL-SYD🇦🇺$849,260,322
EmiratesLHR-DXB🇬🇧🇦🇪$796,201,645
Singapore AirlinesLHR-SIN🇬🇧🇸🇬$735,597,614
United AirlinesSFO-EWR🇺🇸$689,371,368
American AirlinesLAX-JFK🇺🇸$661,739,368
Qatar AirwaysLHR-DOH🇬🇧🇶🇦$639,122,609
Cathay Pacific AirwaysHKG-LHR🇭🇰🇬🇧$604,595,063
Singapore AirlinesSYD-SIN🇦🇺🇸🇬$549,711,946
Air CanadaYVR-YYZ🇨🇦$541,122,509

Air Canada’s route between Vancouver and Toronto bottoms out the list with $541 million of revenue in 2019. Low population density, high infrastructure costs, and an aviation industry that is essentially an oligopoly, are all factors driving up ticket costs in Canada.

North America, Top 10 Highest Revenue Routes by Airline

Here’s a look at only the top-grossing routes connected to North America, including the prior ones that made the global list.

AirlineAirport PairCountriesTotal Revenue US$ 2018/19
British AirwaysJFK-LHR🇺🇸🇬🇧$1,159,126,794
United AirlinesSFO-EWR🇺🇸$689,371,368
American AirlinesLAX-JFK🇺🇸$661,739,788
Air CanadaYVR-YYZ🇨🇦$541,122,509
British AirwaysBOS-LHR🇺🇸🇬🇧$523,527,241
Air FranceJFK-CDG🇺🇸🇫🇷$486,378,698
United AirlinesLAX-EWR🇺🇸$479,908,312
Cathay Pacific AirwaysJFK-HKG🇺🇸🇭🇰$475,514,451
Delta Air LinesLAX-JFK🇺🇸$465,130,366
British AirwaysLAX-LHR🇺🇸🇬🇧$452,136,502

Transcontinental routes dominate the domestic market with LAX–JFK appearing twice in the ranking for both American and Delta Air Lines.

Asia, Top 10 Highest Revenue Routes by Airline

Despite Asia’s rise as an economic superpower, there are no routes that break the billion dollar barrier. Singapore Airlines’ Singapore (SIN) to London’s Heathrow (LHR) tops the list, generating $736 million in 2019.

AirlineAirport PairCountriesTotal Revenue US$ 2018/19
Singapore AirlinesSIN-LHR🇸🇬🇬🇧$735,597,614
Cathay Pacific AirlinesHKG-LHR🇭🇰🇬🇧$604,595,063
Singapore AirlinesSIN-SYD🇸🇬🇦🇺$549,711,946
Vietnam AirlinesSGN-HAN🇻🇳$488,487,259
Cathay Pacific AirlinesHKG-JFK🇭🇰🇺🇸$475,514,451
Japan AirlinesOKA-HND🇯🇵$447,224,346
Singapore AirlinesCGK-SIN🇮🇩🇸🇬$436,905,694
Japan AirlinesFUK-HND🇯🇵$431,457,469
Singapore AirlinesSIN-MEL🇸🇬🇦🇺$414,276,407
Cathay Pacific AirlinesHKG-SIN🇭🇰🇸🇬$389,910,239

The routes that dominate Asia connect the financial hubs of London, New York, Singapore, and Hong Kong. There are also two domestic routes in Japan, connecting both Fukuoka (FUK) and Okinawa (OKA) to Tokyo’s Haneda (HND) airport.

Africa, Top 10 Highest Revenue Routes by Airline

At the top of the ranking in Africa is Johannesburg (JNB) to Dubai International Airport (DXB) with revenues of $315 million. Dubai has become an important hub for high value flights arriving and departing Africa, a position that may prove profitable as air traffic on the continent increases in coming years.

AirlineAirport PairCountriesTotal Revenue US$ 2018/19
EmiratesJNB-DXB🇿🇦🇦🇪$315,678,326
British AirwaysJNB-LHR🇿🇦🇬🇧$295,167,492
Saudi Arabian AirlinesCAI-JED🇪🇬🇸🇦$242,155,949
TAAG Angola AirlinesLAD-LIS🇦🇴🇵🇹$231,155,949
South African AirlinesJNB-CPT🇿🇦$184,944,128
EmiratesCAI-DXB🇪🇬🇦🇪$181,392,011
EmiratesCPT-DXB🇿🇦🇦🇪$176,743,498
Air FranceABJ-CDG🇨🇮🇫🇷$174,986,272
British AirwaysCPT-LHR🇿🇦🇬🇧$174,605,201
EmiratesMRU-DXB🇲🇺🇦🇪$163,952,609

Despite the smaller earnings compared to larger markets, some airline companies see the potential for growth in Africa. Virgin Atlantic will fly a route between London’s Heathrow and Cape Town in South Africa, while Qatar Airlines acquired a stake in RwandAir.

Financial Hubs

The cities that appear in the top revenue ranking are revealing. Since business and first class travelers are such an important revenue driver, it makes sense that connections between the world’s financial hubs are delivering big value to airlines.

As Asian and African economies continue to evolve, what route could be the next billion dollar route for airlines?

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Healthcare

Visualizing the World’s Biggest Pharmaceutical Companies

The world’s biggest pharmaceutical companies are worth $4.1 trillion. Here we map the top 100 companies based on their market cap value.

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Bubble map of the largest pharmaceutical companies in the world

Who are the World’s Biggest Pharmaceutical Companies?

Some of the world’s biggest pharmaceutical companies have played a central role in the COVID-19 pandemic.

However, it’s likely no surprise that the pandemic has also been great for many healthcare businesses. In fact, in 2020 alone, the world’s 50 largest pharmaceutical companies still combined for a whopping $851 billion in revenues.

In this graphic, using data from Companies Market Cap, we list the largest pharmaceutical companies in the world by market capitalization. It’s worth noting this list also includes healthcare companies that work closely with pharmaceuticals, including biotech, pharmaceutical retailers, clinical laboratories, etc.

Editor’s Note: A previous version of this graphic was missing some key companies such as GSK and AbbVie. They were unfortunately not included in the original source and we are now working to make sure there were no other smaller omissions. Thanks to all that sent in corrections.

The Pharmaceutical Leaders

To start, here are the top five biggest pharmaceutical companies in the world at the moment by market capitalization:

1. Johnson & Johnson

The pharmaceutical and consumer goods giant is worth $428.7 billion in market cap. They developed the third vaccine authorized for use in the U.S. and were named among the TIME100 Most Influential Companies List in 2021.

2. Roche

The Swiss pharmaceutical giant is at the forefront of oncology, immunology, infectious diseases, ophthalmology, and neuroscience. In 2019, Roche’s pharma segment sales rose by a healthy 16% to $53 billion.

3. Pfizer

Despite being the leading COVID-19 vaccine manufacturer in North America, Pfizer slid in the rankings to third place. The company has recently gained momentum, especially in the past quarter, with Q2’2021 revenues of $19.0 billion, reflecting a 86% operational growth from 2020.

4. Eli Lilly

Eli Lilly has taken a significant step towards establishing itself as a pharmaceutical industry leader. Having a market cap value of $125 billion in 2019, Eli Lilly has jumped to a current value of $214.9 billion, a significant growth of 72%.

5. Novartis

The second-biggest pharmaceutical company out of Switzerland, Novartis has been the face of the pharma industry for about 25 years. The primary manufacturer for the most recognizable drugs on the market pulled in a revenue of over $48 billion in 2020, a 3% increase compared to 2019.

Here’s how all the biggest pharmaceutical companies in the world stack up against each other:

Company Rank Company NameMarket Cap ValueCountry
1Johnson & Johnson
JNJ
$428.66 B🇺🇸 USA
2Roche
RHHBY
$320.41 B🇨🇭 Switzerland
3Pfizer
PFE
$219.39 B🇺🇸 USA
4Eli Lilly
LLY
$208.99 B🇺🇸 USA
5Novartis
NVS
$207.70 B🇨🇭 Switzerland
6AbbVie
ABBV
$202.60 B🇺🇸 USA
7Merck
MRK
$191.67 B🇺🇸 USA
8Novo Nordisk
NVO
$187.83 B🇩🇰 Denmark
9Astrazeneca
AZN
$152.28 B🇬🇧 UK
10Bristol-Myers Squibb
BMY
$145.80 B🇺🇸 USA
11Amgen
AMGN
$136.50 B🇺🇸 USA
12Sanofi
SNY
$130.37 B🇫🇷 France
13CVS Health
CVS
$110.49 B🇺🇸 USA
14GlaxoSmithKline
GSK
$104.30 B🇬🇧 UK
15CSL
CSL.AX
$103.10 B🇦🇺 Australia
16Gilead Sciences
GILD
$83.62 B🇺🇸 USA
17Moderna
MRNA
$83.25 B🇺🇸 USA
18Merck KGaA
MRK.DE
$80.61 B🇩🇪 Germany
19Bayer
BAYZF
$59.43 B🇩🇪 Germany
20Jiangsu Hengrui Medicine
600276.SS
$58.51 B🇨🇳 China
21Regeneron Pharmaceuticals
REGN
$55.83 B🇺🇸 USA
22Biogen
BIIB
$55.00 B🇺🇸 USA
23BioNTech
BNTX
$54.23 B🇩🇪 Germany
24Takeda Pharmaceutical
TAK
$52.67 B🇯🇵 Japan
25Lonza
LONN.SW
$52.16 B🇨🇭 Switzerland
26Walgreens Boots Alliance
WBA
$45.05 B🇺🇸 USA
27Celltrion
068270.KS
$33.80 B🇰🇷 S. Korea
28Astellas Pharma
ALPMF
$33.42 B🇯🇵 Japan
29BeiGene
BGNE
$31.65 B🇨🇳 China
30Eisai
4523.T
$31.20 B🇯🇵 Japan
31West Pharma
WST
$26.59 B🇺🇸 USA
32Hansoh Pharma
3692.HK
$26.00 B🇨🇳 China
33LabCorp
LH
$25.97 B🇺🇸 USA
34Otsuka Holdings
4578.T
$23.15 B🇯🇵 Japan
35Horizon Therapeutics
HZNP
$21.13 B🇮🇪 Ireland
36Alnylam Pharmaceuticals
ALNY
$20.42 B🇺🇸 USA
37kyowa Kirin
4151.T
$18.85 B🇯🇵 Japan
38Catalent
CTLT
$18.74 B🇺🇸 USA
39Sino Biopharmaceutical
1177.HK
$18.48 B🇭🇰 Hong Kong
40Bio-Techne
TECH
$17.25 B🇺🇸 USA
41PPD
PPD
$16.26 B🇺🇸 USA
42Argenx
ARGX
$16.03 B🇳🇱 Netherlands
43Shionogi
4507.T
$15.29 B🇯🇵 Japan
44Dr. Reddy's
RDY
$11.88 B🇮🇳 India
45Teva Pharmaceutical Industries
TEVA
$11.21 B🇮🇱 Israel
46Ono Pharmaceutical
4528.T
$11.12 B🇯🇵 Japan
47ICON plc
ICLR
$11.09 B🇮🇪 Ireland
48Bausch Health
BHC
$10.47 B🇨🇦 Canada
49CRISPR Therapeutics
CRSP
$10.42 B🇨🇭 Switzerland
50Curevac
CVAC
$10.33 B🇩🇪 Germany
51Hualan Biological Engineering
002007.SZ
$10.31 B🇨🇳 China
52Vifor Pharma
VIFN.SW
$9.49 B🇨🇭 Switzerland
53Neurocrine Biosciences
NBIX
$9.45 B🇺🇸 USA
54Sinopharm
1099.HK
$9.42 B🇨🇳 China
55BridgeBio Pharma
BBIO
$8.89 B🇺🇸 USA
56Cadila Healthcare
CADILAHC.NS
$8.59 B🇮🇳 India
57Sumitomo Dainippon Pharma
4506.T
$8.16 B🇯🇵 Japan
58Tilray
TLRY
$7.89 B🇨🇦 Canada
59Ascendis Pharma
ASND
$7.51 B🇩🇰 Denmark
60Evotec
EVT.F
$7.19 B🇩🇪 Germany
61Lupin Limited
LUPIN.NS
$7.04 B🇮🇳 India
62Gland Pharma
GLAND.NS
$7.01 B🇮🇳 India
63Exelixis
EXEL
$6.95 B🇺🇸 USA
64GW Pharmaceuticals
GWPH
$6.81 B🇬🇧 UK
65KOBAYASHI Pharmaceutical
4967.T
$6.78 B🇯🇵 Japan
66Torrent Pharmaceuticals
TORNTPHARM.NS
$6.61 B🇮🇳 India
67Biocon
BIOCON.NS
$6.43 B🇮🇳 India
68PeptiDream
4587.T
$6.32 B🇯🇵 Japan
69Sarepta Therapeutics
SRPT
$6.25 B🇺🇸 USA
70Perrigo
PRGO
$6.21 B🇮🇪 Ireland
71Orion Corporation
ORNAV.HE
$6.11 B🇫🇮 Finland
72Lundbeck
LDB.F
$6.04 B🇩🇰 Denmark
73AbCellera
ABCL
$5.87 B🇨🇦 Canada
74Adaptive Biotechnologies
ADPT
$5.69 B🇺🇸 USA
75Intellia Therapeutics
NTLA
$5.62 B🇺🇸 USA
76Santen Pharmaceutical
4536.T
$5.49 B🇯🇵 Japan
77Nippon Shinyaku
4516.T
$5.46 B🇯🇵 Japan
78Beam Therapeutics
BEAM
$5.43 B🇺🇸 USA
79Reata Pharmaceuticals
RETA
$5.15 B🇺🇸 USA
80Swedish Orphan Biovitrum
SOBI.ST
$5.13 B🇸🇪 Sweden
81BB Biotech
BION.SW
$5.08 B🇨🇭 Switzerland
82Alkem Laboratories
ALKEM.NS
$5.00 B🇮🇳 India
83Abbott India
ABBOTINDIA.NS
$4.69 B🇮🇳 India
84Laurus Labs
LAURUSLABS.NS
$4.44 B🇮🇳 India
85Taisho Pharmaceutical
4581.T
$4.39 B🇯🇵 Japan
86Hanmi Pharmaceutical
008930.KS
$4.22 B🇰🇷 S. Korea
87Alkermes
ALKS
$3.87 B🇮🇪 Ireland
88Karuna Therapeutics
KRTX
$3.71 B🇺🇸 USA
89Shinpoong Pharm
019170.KS
$3.65 B🇰🇷 S. Korea
90NantKwest
NK
$3.55 B🇺🇸 USA
91Ipca Laboratories
IPCALAB.NS
$3.41 B🇮🇳 India
92Nektar Therapeutics
NKTR
$3.02 B🇺🇸 USA
93BioCryst Pharmaceuticals
BCRX
$3.01 B🇺🇸 USA
94Vericel
VCEL
$2.96 B🇺🇸 USA
95Dicerna Pharmaceuticals
DRNA
$2.84 B🇺🇸 USA
96Rocket Pharmaceuticals
RCKT
$2.74 B🇺🇸 USA
97Axsome Therapeutics
AXSM
$2.65 B🇺🇸 USA
98Natco Pharma
NATCOPHARM.NS
$2.63 B🇮🇳 India
99Alembic Pharmaceuticals
APLLTD.NS
$2.59 B🇮🇳 India
100Editas Medicine
EDIT
$2.54 B🇺🇸 USA

World’s Largest Pharmaceutical Exporters and Importers

According to the World Trade Organization (WTO), these countries exported the most number of pharmaceuticals in the year 2019:

RankCountryExport Value (US$B)
1🇩🇪 Germany$91.4
2🇨🇭 Switzerland$84.8
3🇺🇸 U.S.$55.7
4🇧🇪 Belgium$55.7
5🇮🇪 Ireland$55.4

In contrast, here are the biggest importers over the same period.

RankCountryImport Value (US$B)
1🇺🇸 U.S.$132.4
2🇩🇪 Germany$59.4
3🇧🇪 Belgium$47.3
4🇨🇳 China$35.7
5🇳🇱 Netherlands$33.5

This position is hardly surprising for the U.S., where six of the world’s top 10 pharmaceutical companies are headquartered. The country also captures 45% of the global market.

The Future of Pharmaceutical Companies

If the response to the COVID-19 pandemic has taught us anything, it is that in building a patient-centered future, the pharmaceutical industry plays a key role. It has to constantly find new ways to customize medicines while researching and developing new tools and drugs.

By embracing disruptive technologies like 3D printed drugs, artificial intelligence guided therapies, and preventive medicine while working with regulatory agencies, the pharmaceutical companies will benefit from having a digital revolution.

Furthermore, emerging markets will have a more significant say in the global pharmaceutical market in the coming years. Even though ‘big pharma’ will keep raking in the massive profits they do every year, their reliance on countries like Brazil and India for research and drug production will significantly impact the years to come.

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Markets

Mapping The Biggest Companies By Market Cap in 60 Countries

Tech, finance or energy giant? We mapped the biggest companies by market cap and industry.

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Mapping The Biggest Companies By Market Cap in 60 Countries Share

The Biggest Companies By Market Cap in 60 Countries

Tech giants are increasingly making up more of the Fortune 500, but the world’s biggest companies by market cap aren’t so cut and dry.

Despite accounting for the largest market caps worldwide—with trillion-dollar companies like Apple and contenders including Tencent and Samsung—tech wealth is largely concentrated in just a handful of countries.

So what are the biggest companies in each country? We mapped the largest company by market cap across 60 countries in August 2021 using market data from CompaniesMarketCap, TradingView, and MarketScreener.

What are the Largest Companies in the World?

The world has 60+ stock exchanges, and each one has a top company. We looked at the largest local company, since many of the world’s largest firms trade on multiple exchanges, and converted market cap to USD.

CountryCompanyIndustryMarket Cap (August 2021)
USAAppleTechnology$2.5T
Saudi ArabiaSaudi AramcoEnergy$1.9T
TaiwanTSMCTechnology$594.5B
ChinaTencentTechnology$554.0B
South KoreaSamsungTechnology$429.7B
FranceLVMHConsumer Cyclical$414.3B
SwitzerlandRocheHealthcare$350.0B
NetherlandsASMLTechnology$322.6B
JapanToyotaConsumer Cyclical$251.6B
DenmarkNovo NordiskHealthcare$236.7B
IrelandAccentureTechnology$208.2B
IndiaReliance IndustriesEnergy$198.1B
AustraliaBHP GroupMaterials$191.7B
CanadaShopifyTechnology$185.7B
UKAstrazenecaHealthcare$182.0B
GermanySAPTechnology$174.6B
SingaporeSEATechnology$152.3B
Hong KongAIAFinancials$146.4B
BelgiumAnheuser-Busch InbevConsumer Staples$122.7B
SpainInditexConsumer Cyclical$108.3B
BrazilVALEMaterials$103.9B
RussiaSberbankFinancials$96.7B
ItalyEnelUtilities$93.7B
ArgentinaMercadoLibreConsumer Cyclical$89.5B
SwedenAtlas CopcoIndustrials$84.1B
South AfricaNaspersTechnology$74.1B
NorwayEquinorEnergy$67.9B
UAEEtisalatCommunication$58.7B
MexicoWalmexConsumer Staples$58.1B
IndonesiaBank Cental AsiaFinancials$54.8B
KazakhstanKaspi.kzFinancials$49.8B
QatarQNBFinancials$48.2B
FinlandNordea BankFinancials$48.0B
LuxembourgArcelorMittalMaterials$36.3B
AustriaVerbundUtilities$33.7B
ThailandPTT PCLEnergy$30.1B
ColombiaEcopetrolEnergy$26.7B
MalaysiaMaybankFinancials$23.7B
PhilippinesSM InvestmentsConsumer Cyclical$22.9B
KuwaitKuwait Finance HouseFinancials$21.9B
PortugalEDP GroupUtilities$21.0B
VietnamVinhomesReal Estate$17.1B
IsraelNICETechnology$16.9B
KenyaSafaricomCommunication$16.0B
Czech RepublicÄŒEZ GroupEnergy$15.8B
New ZealandXeroTechnology$15.8B
TurkeyQNB FinansbankFinancials$15.8B
HungaryOTP BankFinancials$15.6B
ChileEnel AmericasUtilities$14.3B
MoroccoMaroc TelecomCommunication$13.6B
PolandPKO Bank PolskiFinancials$12.6B
CyprusPolymetalMaterials$10.0B
NigeriaDangote GroupMaterials$10.0B
BahrainAhli United BankFinancials$8.6B
GreeceOTE GroupCommunication$8.4B
PeruCredicorpFinancials$8.0B
EgyptCommercial International BankFinancials$5.9B
IcelandMarelIndustrials$5.8B
OmanBank MuscatFinancials$4.2B
PanamaCopa HoldingsIndustrials$3.1B

Many are former monopolies or massive conglomerates that have grown in the public space, such as South Africa’s Naspers and India’s Reliance Industries.

Others are local subsidiaries of foreign corporations, including Mexico’s Walmex, Chile’s Enel and Turkey’s QNB Finansbank.

But even more noticeable is the economic discrepancy. Apple and Saudi Aramco are worth trillions of dollars, while the smallest companies we tracked—including Panama’s Copa Group and Oman’s Bank Muscat—are worth less than $5 billion.

Finance and Tech Dominate The Biggest Companies By Market Cap

Across the board, the largest companies were able to accumulate wealth and value.

Some are newer to the top thanks to recent success. Canada’s Shopify has become one of the world’s largest e-commerce providers, and the UK’s AstraZeneca developed one of the world’s COVID-19 vaccines.

But the reality is most companies here are old guards that grew on existing resources, or in the case of banks, accumulated wealth.

IndustryBiggest Companies by Country
Financials16
Technology12
Energy6
Materials5
Communication4
Consumer Cyclical4
Utilities4
Healthcare3
Industrials3
Consumer Staples2
Real Estate1

Banks were the most commonly found at the top of each country’s stock market. Closely behind were oil and gas giants, mining companies, and former state-owned corporations that drove most of a country’s wealth generation.

But as more economies develop and catch up to Western economies (where tech is dominant), newer innovative companies will likely put up a fight for each country’s top company crown.

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