Who are the World’s Biggest Pharmaceutical Companies?
Some of the world’s biggest pharmaceutical companies have played a central role in the COVID-19 pandemic.
However, it’s likely no surprise that the pandemic has also been great for many healthcare businesses. In fact, in 2020 alone, the world’s 50 largest pharmaceutical companies still combined for a whopping $851 billion in revenues.
In this graphic, using data from Companies Market Cap, we list the largest pharmaceutical companies in the world by market capitalization. It’s worth noting this list also includes healthcare companies that work closely with pharmaceuticals, including biotech, pharmaceutical retailers, clinical laboratories, etc.
Editor’s Note: A previous version of this graphic was missing some key companies such as GSK and AbbVie. They were unfortunately not included in the original source and we are now working to make sure there were no other smaller omissions. Thanks to all that sent in corrections.
The Pharmaceutical Leaders
To start, here are the top five biggest pharmaceutical companies in the world at the moment by market capitalization:
1. Johnson & Johnson
The pharmaceutical and consumer goods giant is worth $428.7 billion in market cap. They developed the third vaccine authorized for use in the U.S. and were named among the TIME100 Most Influential Companies List in 2021.
The Swiss pharmaceutical giant is at the forefront of oncology, immunology, infectious diseases, ophthalmology, and neuroscience. In 2019, Roche’s pharma segment sales rose by a healthy 16% to $53 billion.
Despite being the leading COVID-19 vaccine manufacturer in North America, Pfizer slid in the rankings to third place. The company has recently gained momentum, especially in the past quarter, with Q2’2021 revenues of $19.0 billion, reflecting a 86% operational growth from 2020.
4. Eli Lilly
Eli Lilly has taken a significant step towards establishing itself as a pharmaceutical industry leader. Having a market cap value of $125 billion in 2019, Eli Lilly has jumped to a current value of $214.9 billion, a significant growth of 72%.
The second-biggest pharmaceutical company out of Switzerland, Novartis has been the face of the pharma industry for about 25 years. The primary manufacturer for the most recognizable drugs on the market pulled in a revenue of over $48 billion in 2020, a 3% increase compared to 2019.
Here’s how all the biggest pharmaceutical companies in the world stack up against each other:
|Company Rank||Company Name||Market Cap Value||Country|
|1||Johnson & Johnson|
|$428.66 B||🇺🇸 USA|
|$320.41 B||🇨🇭 Switzerland|
|$219.39 B||🇺🇸 USA|
|$208.99 B||🇺🇸 USA|
|$207.70 B||🇨🇭 Switzerland|
|$202.60 B||🇺🇸 USA|
|$191.67 B||🇺🇸 USA|
|$187.83 B||🇩🇰 Denmark|
|$152.28 B||🇬🇧 UK|
|$145.80 B||🇺🇸 USA|
|$136.50 B||🇺🇸 USA|
|$130.37 B||🇫🇷 France|
|$110.49 B||🇺🇸 USA|
|$104.30 B||🇬🇧 UK|
|$103.10 B||🇦🇺 Australia|
|$83.62 B||🇺🇸 USA|
|$83.25 B||🇺🇸 USA|
|$80.61 B||🇩🇪 Germany|
|$59.43 B||🇩🇪 Germany|
|20||Jiangsu Hengrui Medicine |
|$58.51 B||🇨🇳 China|
|$55.83 B||🇺🇸 USA|
|$55.00 B||🇺🇸 USA|
|$54.23 B||🇩🇪 Germany|
|$52.67 B||🇯🇵 Japan|
|$52.16 B||🇨🇭 Switzerland|
|26||Walgreens Boots Alliance|
|$45.05 B||🇺🇸 USA|
|$33.80 B||🇰🇷 S. Korea|
|$33.42 B||🇯🇵 Japan|
|$31.65 B||🇨🇳 China|
|$31.20 B||🇯🇵 Japan|
|$26.59 B||🇺🇸 USA|
|32||Hansoh Pharma |
|$26.00 B||🇨🇳 China|
|$25.97 B||🇺🇸 USA|
|34||Otsuka Holdings |
|$23.15 B||🇯🇵 Japan|
|35||Horizon Therapeutics |
|$21.13 B||🇮🇪 Ireland|
|36||Alnylam Pharmaceuticals |
|$20.42 B||🇺🇸 USA|
|$18.85 B||🇯🇵 Japan|
|$18.74 B||🇺🇸 USA|
|$18.48 B||🇭🇰 Hong Kong|
|$17.25 B||🇺🇸 USA|
|$16.26 B||🇺🇸 USA|
|$16.03 B||🇳🇱 Netherlands|
|$15.29 B||🇯🇵 Japan|
|$11.88 B||🇮🇳 India|
|45||Teva Pharmaceutical Industries|
|$11.21 B||🇮🇱 Israel|
|46||Ono Pharmaceutical |
|$11.12 B||🇯🇵 Japan|
|$11.09 B||🇮🇪 Ireland|
|48||Bausch Health |
|$10.47 B||🇨🇦 Canada|
|$10.42 B||🇨🇭 Switzerland|
|$10.33 B||🇩🇪 Germany|
|51||Hualan Biological Engineering|
|$10.31 B||🇨🇳 China|
|$9.49 B||🇨🇭 Switzerland|
|53||Neurocrine Biosciences |
|$9.45 B||🇺🇸 USA|
|$9.42 B||🇨🇳 China|
|55||BridgeBio Pharma |
|$8.89 B||🇺🇸 USA|
|56||Cadila Healthcare |
|$8.59 B||🇮🇳 India|
|57||Sumitomo Dainippon Pharma |
|$8.16 B||🇯🇵 Japan|
|$7.89 B||🇨🇦 Canada|
|59||Ascendis Pharma |
|$7.51 B||🇩🇰 Denmark|
|$7.19 B||🇩🇪 Germany|
|61||Lupin Limited |
|$7.04 B||🇮🇳 India|
|62||Gland Pharma |
|$7.01 B||🇮🇳 India|
|$6.95 B||🇺🇸 USA|
|64||GW Pharmaceuticals |
|$6.81 B||🇬🇧 UK|
|$6.78 B||🇯🇵 Japan|
|66||Torrent Pharmaceuticals |
|$6.61 B||🇮🇳 India|
|$6.43 B||🇮🇳 India|
|$6.32 B||🇯🇵 Japan|
|69||Sarepta Therapeutics |
|$6.25 B||🇺🇸 USA|
|$6.21 B||🇮🇪 Ireland|
|$6.11 B||🇫🇮 Finland|
|$6.04 B||🇩🇰 Denmark|
|$5.87 B||🇨🇦 Canada|
|74||Adaptive Biotechnologies |
|$5.69 B||🇺🇸 USA|
|75||Intellia Therapeutics |
|$5.62 B||🇺🇸 USA|
|76||Santen Pharmaceutical |
|$5.49 B||🇯🇵 Japan|
|$5.46 B||🇯🇵 Japan|
|78||Beam Therapeutics |
|$5.43 B||🇺🇸 USA|
|79||Reata Pharmaceuticals |
|$5.15 B||🇺🇸 USA|
|80||Swedish Orphan Biovitrum|
|$5.13 B||🇸🇪 Sweden|
|81||BB Biotech |
|$5.08 B||🇨🇭 Switzerland|
|82||Alkem Laboratories |
|$5.00 B||🇮🇳 India|
|$4.69 B||🇮🇳 India|
|84||Laurus Labs |
|$4.44 B||🇮🇳 India|
|85||Taisho Pharmaceutical |
|$4.39 B||🇯🇵 Japan|
|86||Hanmi Pharmaceutical |
|$4.22 B||🇰🇷 S. Korea|
|$3.87 B||🇮🇪 Ireland|
|$3.71 B||🇺🇸 USA|
|$3.65 B||🇰🇷 S. Korea|
|$3.55 B||🇺🇸 USA|
|91||Ipca Laboratories |
|$3.41 B||🇮🇳 India|
|92||Nektar Therapeutics |
|$3.02 B||🇺🇸 USA|
|93||BioCryst Pharmaceuticals |
|$3.01 B||🇺🇸 USA|
|$2.96 B||🇺🇸 USA|
|$2.84 B||🇺🇸 USA|
|96||Rocket Pharmaceuticals |
|$2.74 B||🇺🇸 USA|
|97||Axsome Therapeutics |
|$2.65 B||🇺🇸 USA|
|98||Natco Pharma |
|$2.63 B||🇮🇳 India|
|$2.59 B||🇮🇳 India|
|100||Editas Medicine |
|$2.54 B||🇺🇸 USA|
World’s Largest Pharmaceutical Exporters and Importers
According to the World Trade Organization (WTO), these countries exported the most number of pharmaceuticals in the year 2019:
|Rank||Country||Export Value (US$B)|
In contrast, here are the biggest importers over the same period.
|Rank||Country||Import Value (US$B)|
This position is hardly surprising for the U.S., where six of the world’s top 10 pharmaceutical companies are headquartered. The country also captures 45% of the global market.
The Future of Pharmaceutical Companies
If the response to the COVID-19 pandemic has taught us anything, it is that in building a patient-centered future, the pharmaceutical industry plays a key role. It has to constantly find new ways to customize medicines while researching and developing new tools and drugs.
By embracing disruptive technologies like 3D printed drugs, artificial intelligence guided therapies, and preventive medicine while working with regulatory agencies, the pharmaceutical companies will benefit from having a digital revolution.
Furthermore, emerging markets will have a more significant say in the global pharmaceutical market in the coming years. Even though ‘big pharma’ will keep raking in the massive profits they do every year, their reliance on countries like Brazil and India for research and drug production will significantly impact the years to come.
Visualizing The Most Widespread Blood Types in Every Country
There are 8 common blood groups but 36 human blood types in total. Here we map the most widespread blood types in every country in the world.
The Most Widespread Blood Types, by Country
Blood is essential to the human body’s functioning. It dispenses crucial nutrients throughout the body, exchanges oxygen and carbon dioxide, and carries our immune system’s “militia” of white blood cells and antibodies to stave off infections.
But not all blood is the same. The antigens in one’s blood determine their blood type classification: There are eight common blood type groups, and with different combinations of antigens and classifications, 36 human blood type groups in total.
Using data sourced from Wikipedia, we can map the most widespread blood types across the globe.
Overall Distribution of Blood Types
Of the 7.9 billion people living in the world, spread across 195 countries and 7 continents, the most common blood type is O+, with over 39% of the world’s population falling under this classification. The rarest, meanwhile, is AB-, with only 0.40% of the population having this particular blood type.
Breaking it down to the national level, these statistics begin to change. Since different genetic factors play a part in determining an individual’s blood type, every country and region tells a different story about its people.
Regional Distribution of Blood Types
Even though O+ remains the most common blood type here, blood type B is relatively common too. Nearly 20% of China’s population has this blood type, and it is also fairly common in India and other Central Asian countries.
Comparatively, in some West Asian countries like Armenia and Azerbaijan, the population with blood type A+ outweighs any others.
The O blood type is the most common globally and is carried by nearly 70% of South Americans. It is also the most common blood type in Canada and the United States.
Here is a breakdown of the most common blood types in the U.S. by race:
O+ is a strong blood group classification among African countries. Countries like Ghana, Libya, Congo and Egypt, have more individuals with O- blood types than AB+.
The A blood group is common in Europe. Nearly 40% of Denmark, Norway, Austria, and Ukraine have this blood type.
O+ and A+ are dominant blood types in the Oceanic countries, with only Fiji having a substantial B+ blood type population.
More than 41% of the population displays the O+ blood group type, with Lebanon being the only country with a strong O- and A- blood type population.
Nearly half of people in Caribbean countries have the blood type O+, though Jamaica has B+ as the most common blood type group.
Here is the classification of the blood types by every region in the world:
Unity in Diversity
Even though ethnicity and genetics play a vital role in determining a person’s blood type, we can see many different blood types distributed worldwide.
Blood provides an ideal opportunity for the study of human variation without cultural prejudice. It can be easily classified for many different genetically inherited blood typing systems.
Our individuality is a factor that helps determine our life, choices, and personalities. But at the end of the day, commonalities like blood are what bring us together.
Pandemic Recovery: Have North American Downtowns Bounced Back?
All North American downtowns are facing a sluggish recovery, but some are still seeing more than 80% less foot traffic than pre-pandemic times
Pandemic Recovery: Have Downtowns Bounced Back?
As we continue on our journey towards recovery from the impacts of the pandemic, North American offices that sat empty for months have started to welcome back in-person workers.
This small step towards normalcy has sparked questions around the future of office life—will office culture eventually bounce back to pre-pandemic levels, or is remote work here to stay?
It’s impossible to predict the future, but one way to gauge the current state of office life is by looking at foot traffic across city centers in North America. This graphic measures just that, using data from Avison Young.
Change in Downtown Office Traffic
According to the data, which measures foot traffic in major office buildings in 23 different metropolitan hubs across North America, remains drastically below pre-pandemic levels.
Across all major cities included in the index, average weekday visitor volume has fallen by 73.7% since the early months of 2020. Here’s a look at each individual city’s change in foot traffic, from March 2, 2020 to Oct 11, 2021:
|City||Country||Change in Foot Traffic|
|San Francisco Peninsula||🇺🇸||-70.00%|
The Canadian city of Calgary is a somewhat unique case. On one hand, foot traffic has bounced back stronger than many other downtowns across North America. On the other hand, the city has one of the highest commercial vacancy rates in North America, and there are existential questions about what comes next for the city.
Interestingly, a number of cities with a high proportion of tech jobs, such as Austin, Boston, and San Francisco bounced back the strongest post-pandemic. Of course, there is one noteworthy exception to that rule.
A Tale of Two Cities
Silicon Valley has experienced one of the most significant drops in foot traffic, at -82.6%. Tech as an industry has seen one of the largest increases in remote work, as Bay Area workers look to escape high commuter traffic and high living expenses. A recent survey found that 53% of tech workers in the region said they are considering moving, with housing costs being the primary reason most respondents cited.
Meanwhile, in a very different part of North America, another city is experienced a sluggish rebound in foot traffic, but for very different reasons. Ottawa, Canada’s capital, is facing empty streets and struggling small businesses that rely on the droves of government workers that used to commute to downtown offices. Unlike Silicon Valley, where tech workers are taking advantage of flexible work options, many federal workers in Ottawa are still working from home without a clear plan on returning to the workplace.
It’s also worth noting that these two cities are home to a lot of single-occupant office buildings, which is a focus of this data set.
Some Businesses Remain Hopeful
Despite a slow return to office life, some employers are snapping up commercial office space in preparation for a potential mass return to the office.
Back in March 2021, Google announced it was planning to spend over $7 billion on U.S. office space and data centers. The tech giant held true to its promise—in September, Google purchased a Manhattan commercial building for $2.1 billion.
Other tech companies like Alphabet and Facebook have also been growing their office spaces throughout the pandemic. In August 2021, Amazon leased new office space in six major U.S. cities, and in September 2020, Facebook bought a 400,000 square foot complex in Bellevue, Washington.
Will More Employees Return or Stay Remote?
It’s important to note that we’re still in the midst of pandemic recovery, which means the jury’s still out on what our post-pandemic world will look like.
Will different cities and industries eventually recover in different ways, or are we approaching the realities of “new normal” foot traffic in North American city centers?
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