Visualizing America's Entrepreneurial Spirit During COVID-19
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Visualizing America’s Entrepreneurial Spirit During COVID-19

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Mapped: America’s Entrepreneurial Spirit During COVID-19

Despite the risks of opening a business during a global pandemic, new data from the U.S. Census Bureau reveals that the entrepreneurial spirit is alive and well in the United States.

In total, there were 492,133 new business applications in January 2021—an increase of over 73% year-over-year (YoY).

The region with the highest growth rate was the South at 84% with more than 220,000 new business applications in the region in January of this year. Mississippi had the highest percent increase at 164%, with over 6,000 new applications in January 2021.

Here’s a closer look at the number of total applications by state and region:

Notably, new business applications have soared in the last month or so, bouncing back from a dip between July and December 2020.

The growth rate from December 2020 to January 2021 stood at 42.6%, with the biggest change happening in the Midwest, where applications have gone up 48.6%. Here’s a look at the biggest changes in applications by region since December 2020:

RegionNumber of Applications in January 2021Percentage Change from December 2020
Midwest85,50348.6%
Northeast 77,91047.9%
West103,86140.5%
South 224,85939.6%

Note: Business applications are measured by collecting data on new applications for Employer Identification Numbers with the U.S. government.

Opportunity Out of Crisis

Prior to the pandemic, new business startups were actually on the decline, but in times of crisis there is often opportunity.

People have become wildly innovative during COVID-19, partly because they were forced to do so due to job or income loss. Economists call this ‘creative destruction,’ wherein new innovation springs up because of the failure of particular industries or businesses.

Here’s a look at new business applications by industry.

IndustryNumber of New Business Applications (Jan. 2021)
Retail Trade101,842
Professional Services56,280
Construction43,724
Other Services43,511
Transportation and Warehousing 41,320
Administrative Support32,765
Accommodation and Food Services27,409
Health Care and Social Assistance 27,266
Real Estate23,804
Finance and Insurance22,607
Arts and Entertainment14,407
Unclassified 13,442
Wholesale Trade10,298
Information9,907
Manufacturing7,420
Educational Services6,790
Management of Companies 4,273
Agriculture3,978
Mining585
Utilities505

Creative destruction has been keenly exemplified in the rise of remote and digital services over traditional brick and mortar stores. In fact, the industry with the highest number of new business applications in January 2021 was retail services, mostly online, with over 101,000 applications.

Feeling the Entrepreneurial Spirit?

As business applications are on the rise, more jobs could potentially be created in the U.S., and competition will likely increase as well. While starting a business during COVID-19 is risky, it could have immense payoffs for the individuals involved and the overall economy.

In fact, a piece from the U.S. Chamber of Commerce actually recommends specific business ideas that are ‘pandemic-friendly.’ Among many virtually-based ideas, the list includes:

  • Digital marketing
  • App development
  • Fitness and wellness services
  • Box subscription services

Perhaps, for digitally minded entrepreneurs, there has never been a better time to start a business.

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Healthcare

Visualizing the World’s Biggest Pharmaceutical Companies

The world’s biggest pharmaceutical companies are worth $4.1 trillion. Here we map the top 100 companies based on their market cap value.

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Bubble map of the largest pharmaceutical companies in the world

Who are the World’s Biggest Pharmaceutical Companies?

Some of the world’s biggest pharmaceutical companies have played a central role in the COVID-19 pandemic.

However, it’s likely no surprise that the pandemic has also been great for many healthcare businesses. In fact, in 2020 alone, the world’s 50 largest pharmaceutical companies still combined for a whopping $851 billion in revenues.

In this graphic, using data from Companies Market Cap, we list the largest pharmaceutical companies in the world by market capitalization. It’s worth noting this list also includes healthcare companies that work closely with pharmaceuticals, including biotech, pharmaceutical retailers, clinical laboratories, etc.

Editor’s Note: A previous version of this graphic was missing some key companies such as GSK and AbbVie. They were unfortunately not included in the original source and we are now working to make sure there were no other smaller omissions. Thanks to all that sent in corrections.

The Pharmaceutical Leaders

To start, here are the top five biggest pharmaceutical companies in the world at the moment by market capitalization:

1. Johnson & Johnson

The pharmaceutical and consumer goods giant is worth $428.7 billion in market cap. They developed the third vaccine authorized for use in the U.S. and were named among the TIME100 Most Influential Companies List in 2021.

2. Roche

The Swiss pharmaceutical giant is at the forefront of oncology, immunology, infectious diseases, ophthalmology, and neuroscience. In 2019, Roche’s pharma segment sales rose by a healthy 16% to $53 billion.

3. Pfizer

Despite being the leading COVID-19 vaccine manufacturer in North America, Pfizer slid in the rankings to third place. The company has recently gained momentum, especially in the past quarter, with Q2’2021 revenues of $19.0 billion, reflecting a 86% operational growth from 2020.

4. Eli Lilly

Eli Lilly has taken a significant step towards establishing itself as a pharmaceutical industry leader. Having a market cap value of $125 billion in 2019, Eli Lilly has jumped to a current value of $214.9 billion, a significant growth of 72%.

5. Novartis

The second-biggest pharmaceutical company out of Switzerland, Novartis has been the face of the pharma industry for about 25 years. The primary manufacturer for the most recognizable drugs on the market pulled in a revenue of over $48 billion in 2020, a 3% increase compared to 2019.

Here’s how all the biggest pharmaceutical companies in the world stack up against each other:

Company Rank Company NameMarket Cap ValueCountry
1Johnson & Johnson
JNJ
$428.66 B🇺🇸 USA
2Roche
RHHBY
$320.41 B🇨🇭 Switzerland
3Pfizer
PFE
$219.39 B🇺🇸 USA
4Eli Lilly
LLY
$208.99 B🇺🇸 USA
5Novartis
NVS
$207.70 B🇨🇭 Switzerland
6AbbVie
ABBV
$202.60 B🇺🇸 USA
7Merck
MRK
$191.67 B🇺🇸 USA
8Novo Nordisk
NVO
$187.83 B🇩🇰 Denmark
9Astrazeneca
AZN
$152.28 B🇬🇧 UK
10Bristol-Myers Squibb
BMY
$145.80 B🇺🇸 USA
11Amgen
AMGN
$136.50 B🇺🇸 USA
12Sanofi
SNY
$130.37 B🇫🇷 France
13CVS Health
CVS
$110.49 B🇺🇸 USA
14GlaxoSmithKline
GSK
$104.30 B🇬🇧 UK
15CSL
CSL.AX
$103.10 B🇦🇺 Australia
16Gilead Sciences
GILD
$83.62 B🇺🇸 USA
17Moderna
MRNA
$83.25 B🇺🇸 USA
18Merck KGaA
MRK.DE
$80.61 B🇩🇪 Germany
19Bayer
BAYZF
$59.43 B🇩🇪 Germany
20Jiangsu Hengrui Medicine
600276.SS
$58.51 B🇨🇳 China
21Regeneron Pharmaceuticals
REGN
$55.83 B🇺🇸 USA
22Biogen
BIIB
$55.00 B🇺🇸 USA
23BioNTech
BNTX
$54.23 B🇩🇪 Germany
24Takeda Pharmaceutical
TAK
$52.67 B🇯🇵 Japan
25Lonza
LONN.SW
$52.16 B🇨🇭 Switzerland
26Walgreens Boots Alliance
WBA
$45.05 B🇺🇸 USA
27Celltrion
068270.KS
$33.80 B🇰🇷 S. Korea
28Astellas Pharma
ALPMF
$33.42 B🇯🇵 Japan
29BeiGene
BGNE
$31.65 B🇨🇳 China
30Eisai
4523.T
$31.20 B🇯🇵 Japan
31West Pharma
WST
$26.59 B🇺🇸 USA
32Hansoh Pharma
3692.HK
$26.00 B🇨🇳 China
33LabCorp
LH
$25.97 B🇺🇸 USA
34Otsuka Holdings
4578.T
$23.15 B🇯🇵 Japan
35Horizon Therapeutics
HZNP
$21.13 B🇮🇪 Ireland
36Alnylam Pharmaceuticals
ALNY
$20.42 B🇺🇸 USA
37kyowa Kirin
4151.T
$18.85 B🇯🇵 Japan
38Catalent
CTLT
$18.74 B🇺🇸 USA
39Sino Biopharmaceutical
1177.HK
$18.48 B🇭🇰 Hong Kong
40Bio-Techne
TECH
$17.25 B🇺🇸 USA
41PPD
PPD
$16.26 B🇺🇸 USA
42Argenx
ARGX
$16.03 B🇳🇱 Netherlands
43Shionogi
4507.T
$15.29 B🇯🇵 Japan
44Dr. Reddy's
RDY
$11.88 B🇮🇳 India
45Teva Pharmaceutical Industries
TEVA
$11.21 B🇮🇱 Israel
46Ono Pharmaceutical
4528.T
$11.12 B🇯🇵 Japan
47ICON plc
ICLR
$11.09 B🇮🇪 Ireland
48Bausch Health
BHC
$10.47 B🇨🇦 Canada
49CRISPR Therapeutics
CRSP
$10.42 B🇨🇭 Switzerland
50Curevac
CVAC
$10.33 B🇩🇪 Germany
51Hualan Biological Engineering
002007.SZ
$10.31 B🇨🇳 China
52Vifor Pharma
VIFN.SW
$9.49 B🇨🇭 Switzerland
53Neurocrine Biosciences
NBIX
$9.45 B🇺🇸 USA
54Sinopharm
1099.HK
$9.42 B🇨🇳 China
55BridgeBio Pharma
BBIO
$8.89 B🇺🇸 USA
56Cadila Healthcare
CADILAHC.NS
$8.59 B🇮🇳 India
57Sumitomo Dainippon Pharma
4506.T
$8.16 B🇯🇵 Japan
58Tilray
TLRY
$7.89 B🇨🇦 Canada
59Ascendis Pharma
ASND
$7.51 B🇩🇰 Denmark
60Evotec
EVT.F
$7.19 B🇩🇪 Germany
61Lupin Limited
LUPIN.NS
$7.04 B🇮🇳 India
62Gland Pharma
GLAND.NS
$7.01 B🇮🇳 India
63Exelixis
EXEL
$6.95 B🇺🇸 USA
64GW Pharmaceuticals
GWPH
$6.81 B🇬🇧 UK
65KOBAYASHI Pharmaceutical
4967.T
$6.78 B🇯🇵 Japan
66Torrent Pharmaceuticals
TORNTPHARM.NS
$6.61 B🇮🇳 India
67Biocon
BIOCON.NS
$6.43 B🇮🇳 India
68PeptiDream
4587.T
$6.32 B🇯🇵 Japan
69Sarepta Therapeutics
SRPT
$6.25 B🇺🇸 USA
70Perrigo
PRGO
$6.21 B🇮🇪 Ireland
71Orion Corporation
ORNAV.HE
$6.11 B🇫🇮 Finland
72Lundbeck
LDB.F
$6.04 B🇩🇰 Denmark
73AbCellera
ABCL
$5.87 B🇨🇦 Canada
74Adaptive Biotechnologies
ADPT
$5.69 B🇺🇸 USA
75Intellia Therapeutics
NTLA
$5.62 B🇺🇸 USA
76Santen Pharmaceutical
4536.T
$5.49 B🇯🇵 Japan
77Nippon Shinyaku
4516.T
$5.46 B🇯🇵 Japan
78Beam Therapeutics
BEAM
$5.43 B🇺🇸 USA
79Reata Pharmaceuticals
RETA
$5.15 B🇺🇸 USA
80Swedish Orphan Biovitrum
SOBI.ST
$5.13 B🇸🇪 Sweden
81BB Biotech
BION.SW
$5.08 B🇨🇭 Switzerland
82Alkem Laboratories
ALKEM.NS
$5.00 B🇮🇳 India
83Abbott India
ABBOTINDIA.NS
$4.69 B🇮🇳 India
84Laurus Labs
LAURUSLABS.NS
$4.44 B🇮🇳 India
85Taisho Pharmaceutical
4581.T
$4.39 B🇯🇵 Japan
86Hanmi Pharmaceutical
008930.KS
$4.22 B🇰🇷 S. Korea
87Alkermes
ALKS
$3.87 B🇮🇪 Ireland
88Karuna Therapeutics
KRTX
$3.71 B🇺🇸 USA
89Shinpoong Pharm
019170.KS
$3.65 B🇰🇷 S. Korea
90NantKwest
NK
$3.55 B🇺🇸 USA
91Ipca Laboratories
IPCALAB.NS
$3.41 B🇮🇳 India
92Nektar Therapeutics
NKTR
$3.02 B🇺🇸 USA
93BioCryst Pharmaceuticals
BCRX
$3.01 B🇺🇸 USA
94Vericel
VCEL
$2.96 B🇺🇸 USA
95Dicerna Pharmaceuticals
DRNA
$2.84 B🇺🇸 USA
96Rocket Pharmaceuticals
RCKT
$2.74 B🇺🇸 USA
97Axsome Therapeutics
AXSM
$2.65 B🇺🇸 USA
98Natco Pharma
NATCOPHARM.NS
$2.63 B🇮🇳 India
99Alembic Pharmaceuticals
APLLTD.NS
$2.59 B🇮🇳 India
100Editas Medicine
EDIT
$2.54 B🇺🇸 USA

World’s Largest Pharmaceutical Exporters and Importers

According to the World Trade Organization (WTO), these countries exported the most number of pharmaceuticals in the year 2019:

RankCountryExport Value (US$B)
1🇩🇪 Germany$91.4
2🇨🇭 Switzerland$84.8
3🇺🇸 U.S.$55.7
4🇧🇪 Belgium$55.7
5🇮🇪 Ireland$55.4

In contrast, here are the biggest importers over the same period.

RankCountryImport Value (US$B)
1🇺🇸 U.S.$132.4
2🇩🇪 Germany$59.4
3🇧🇪 Belgium$47.3
4🇨🇳 China$35.7
5🇳🇱 Netherlands$33.5

This position is hardly surprising for the U.S., where six of the world’s top 10 pharmaceutical companies are headquartered. The country also captures 45% of the global market.

The Future of Pharmaceutical Companies

If the response to the COVID-19 pandemic has taught us anything, it is that in building a patient-centered future, the pharmaceutical industry plays a key role. It has to constantly find new ways to customize medicines while researching and developing new tools and drugs.

By embracing disruptive technologies like 3D printed drugs, artificial intelligence guided therapies, and preventive medicine while working with regulatory agencies, the pharmaceutical companies will benefit from having a digital revolution.

Furthermore, emerging markets will have a more significant say in the global pharmaceutical market in the coming years. Even though ‘big pharma’ will keep raking in the massive profits they do every year, their reliance on countries like Brazil and India for research and drug production will significantly impact the years to come.

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Markets

Mapping The Biggest Companies By Market Cap in 60 Countries

Tech, finance or energy giant? We mapped the biggest companies by market cap and industry.

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Mapping The Biggest Companies By Market Cap in 60 Countries Share

The Biggest Companies By Market Cap in 60 Countries

Tech giants are increasingly making up more of the Fortune 500, but the world’s biggest companies by market cap aren’t so cut and dry.

Despite accounting for the largest market caps worldwide—with trillion-dollar companies like Apple and contenders including Tencent and Samsung—tech wealth is largely concentrated in just a handful of countries.

So what are the biggest companies in each country? We mapped the largest company by market cap across 60 countries in August 2021 using market data from CompaniesMarketCap, TradingView, and MarketScreener.

What are the Largest Companies in the World?

The world has 60+ stock exchanges, and each one has a top company. We looked at the largest local company, since many of the world’s largest firms trade on multiple exchanges, and converted market cap to USD.

CountryCompanyIndustryMarket Cap (August 2021)
USAAppleTechnology$2.5T
Saudi ArabiaSaudi AramcoEnergy$1.9T
TaiwanTSMCTechnology$594.5B
ChinaTencentTechnology$554.0B
South KoreaSamsungTechnology$429.7B
FranceLVMHConsumer Cyclical$414.3B
SwitzerlandRocheHealthcare$350.0B
NetherlandsASMLTechnology$322.6B
JapanToyotaConsumer Cyclical$251.6B
DenmarkNovo NordiskHealthcare$236.7B
IrelandAccentureTechnology$208.2B
IndiaReliance IndustriesEnergy$198.1B
AustraliaBHP GroupMaterials$191.7B
CanadaShopifyTechnology$185.7B
UKAstrazenecaHealthcare$182.0B
GermanySAPTechnology$174.6B
SingaporeSEATechnology$152.3B
Hong KongAIAFinancials$146.4B
BelgiumAnheuser-Busch InbevConsumer Staples$122.7B
SpainInditexConsumer Cyclical$108.3B
BrazilVALEMaterials$103.9B
RussiaSberbankFinancials$96.7B
ItalyEnelUtilities$93.7B
ArgentinaMercadoLibreConsumer Cyclical$89.5B
SwedenAtlas CopcoIndustrials$84.1B
South AfricaNaspersTechnology$74.1B
NorwayEquinorEnergy$67.9B
UAEEtisalatCommunication$58.7B
MexicoWalmexConsumer Staples$58.1B
IndonesiaBank Cental AsiaFinancials$54.8B
KazakhstanKaspi.kzFinancials$49.8B
QatarQNBFinancials$48.2B
FinlandNordea BankFinancials$48.0B
LuxembourgArcelorMittalMaterials$36.3B
AustriaVerbundUtilities$33.7B
ThailandPTT PCLEnergy$30.1B
ColombiaEcopetrolEnergy$26.7B
MalaysiaMaybankFinancials$23.7B
PhilippinesSM InvestmentsConsumer Cyclical$22.9B
KuwaitKuwait Finance HouseFinancials$21.9B
PortugalEDP GroupUtilities$21.0B
VietnamVinhomesReal Estate$17.1B
IsraelNICETechnology$16.9B
KenyaSafaricomCommunication$16.0B
Czech RepublicÄŒEZ GroupEnergy$15.8B
New ZealandXeroTechnology$15.8B
TurkeyQNB FinansbankFinancials$15.8B
HungaryOTP BankFinancials$15.6B
ChileEnel AmericasUtilities$14.3B
MoroccoMaroc TelecomCommunication$13.6B
PolandPKO Bank PolskiFinancials$12.6B
CyprusPolymetalMaterials$10.0B
NigeriaDangote GroupMaterials$10.0B
BahrainAhli United BankFinancials$8.6B
GreeceOTE GroupCommunication$8.4B
PeruCredicorpFinancials$8.0B
EgyptCommercial International BankFinancials$5.9B
IcelandMarelIndustrials$5.8B
OmanBank MuscatFinancials$4.2B
PanamaCopa HoldingsIndustrials$3.1B

Many are former monopolies or massive conglomerates that have grown in the public space, such as South Africa’s Naspers and India’s Reliance Industries.

Others are local subsidiaries of foreign corporations, including Mexico’s Walmex, Chile’s Enel and Turkey’s QNB Finansbank.

But even more noticeable is the economic discrepancy. Apple and Saudi Aramco are worth trillions of dollars, while the smallest companies we tracked—including Panama’s Copa Group and Oman’s Bank Muscat—are worth less than $5 billion.

Finance and Tech Dominate The Biggest Companies By Market Cap

Across the board, the largest companies were able to accumulate wealth and value.

Some are newer to the top thanks to recent success. Canada’s Shopify has become one of the world’s largest e-commerce providers, and the UK’s AstraZeneca developed one of the world’s COVID-19 vaccines.

But the reality is most companies here are old guards that grew on existing resources, or in the case of banks, accumulated wealth.

IndustryBiggest Companies by Country
Financials16
Technology12
Energy6
Materials5
Communication4
Consumer Cyclical4
Utilities4
Healthcare3
Industrials3
Consumer Staples2
Real Estate1

Banks were the most commonly found at the top of each country’s stock market. Closely behind were oil and gas giants, mining companies, and former state-owned corporations that drove most of a country’s wealth generation.

But as more economies develop and catch up to Western economies (where tech is dominant), newer innovative companies will likely put up a fight for each country’s top company crown.

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