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Comparing THC vs. CBD: What’s the Difference?

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The business of legal cannabis is rapidly growing on both medicinal and recreational fronts. In fact, last year legal cannabis sales soared in the United States to $5.4 billion, a 17.4% increase.

However, cannabis itself is a fairly perplexing substance. It has close to 500 active compounds, and at least 113 of these belong to a family of diverse chemical compounds called cannabinoids.

Of this group, the two most common and researched compounds are THC and CBD – but they are vastly different. As new strains and product offerings become available in the legal cannabis sector, it is more important than ever before for investors to understand the difference between these two compounds.

Comparing THC vs. CBD: What’s the Difference?

The following infographic comes to us from food sciences company Lexaria Bioscience (OTCQB:LXRP) (CSE:LXX) and it shows the key differences between THC and CBD. It provides fundamental knowledge for investors, patients, and regulators that want to better understand this quickly growing sector of business.

THC-vs-CBD-7-(no-outline)-1

In the comparison of THC vs. CBD, it’s clear that the two compounds are vastly different. While they both interact with receptors in the body, they produce different effects.

To start, THC, or tetrahydrocannabinol, is a psychoactive compound while CBD, or cannabidiol, does not affect the mind in the same capacity.

THC has the following effects on a user:

  • Analgesic: Relieves pain and inflammation
  • Relaxing: Creates sense of relaxation and well-being
  • Drowsiness: Induces sleep
  • Euphoria: Creates “high”
  • Appetite Stimulant: Creates urge to eat

While CBD’s medicinal effects are making CBD-heavy strains a popular choice for patients:

  • Anti-inflammatory: Combats inflammation and pain
  • Anticonvulsant: Suppresses seizure activity
  • Antiemetic: Reduces nausea and vomiting
  • Antipsychotic: Combats psychosis
  • Anti-oxidant: Combats neurodegenerative diseases
  • Anti-depressant: Combats anxiety and depression
  • Anti-tumoral: Combats tumor and cancer cells
  • Neuro-protective: May protect neurons in the brain

As a result of these effects, THC is typically used to treat pain, nausea, sleep apnea, or stress disorders, as well as to combat the symptoms or side effects of chemotherapy, multiple sclerosis, glaucoma, AIDS, or spinal injuries.

CBD, on the other hand, is being used to treat inflammation, stress, depression and anxiety, while also being used to combat cancer, epilepsy, schizophrenia, multiple sclerosis, migraines, arthritis, and the side effects of cancer treatments.

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Retail

The World’s Top Retail Companies, by Domestic Revenue

As price pressures and e-commerce reshape shopping behaviors, we show the top retail companies by domestic revenue around the world.

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This circle graphic shows the world's top retail companies by domestic revenue.

The World’s Top Retail Companies, by Domestic Revenue

This was originally posted on our Voronoi app. Download the app for free on iOS or Android and discover incredible data-driven charts from a variety of trusted sources.

The retail sector plays a vital role in powering economies, contributing $5.3 trillion annually to America’s GDP alone.

Moreover, the industry is America’s biggest private-sector employer, responsible for one of every four jobs, or 55 million employees. Yet in today’s challenging consumer environment, retailers are facing higher e-commerce penetration and inflationary pressures—across an industry notoriously known for razor-thin margins.

This graphic shows the world’s top retail companies by domestic revenue, based on data from the National Retail Federation.

Methodology

To be included in the rankings, companies must engage in a goods-for-consumer resale business accessible to the public and have direct selling operations in a minimum of three countries.

The rankings include both publicly and private companies, and are based on the most recent 52-week period analyzed by the National Retail Federation between January and March 2024. All revenue figures were converted to U.S. dollars.

Ranked: The Top 10 Global Retailers by Domestic Sales

Here are the leading retailers worldwide based on domestic sales as of 2023:

RankingRetailerDomestic Retail Revenue
(USD)
Share of Total Retail RevenueHeadquarters
1Walmart$532.3B85%🇺🇸 U.S.
2Amazon.com$250.0B70%🇺🇸 U.S.
3Costco$175.4B75%🇺🇸 U.S.
4The Home Depot$142.0B94%🇺🇸 U.S.
5Walgreens Boots Alliance$105.1B89%🇺🇸 U.S.
6Alibaba$91.5B97%🇨🇳 China
7Apple$70.9B87%🇺🇸 U.S.
8Aeon$64.3B93%🇯🇵 Japan
9Schwarz Group$56.5B32%🇩🇪 Germany
10Rewe$55.5B75%🇩🇪 Germany

Walmart towers ahead as the world’s largest retailer with $532 billion in domestic revenue—more than Amazon.com and Costco combined.

Known for its everyday low prices, Walmart achieves a competitive advantage through pricing goods approximately 25% cheaper than traditional retail competitors. Overall, groceries make up more than half of total sales. While its main customer base is often low and middle-income shoppers, the retail giant is seeing a surge in sales from higher-income customers as shoppers seek out lower grocery prices.

E-commerce giant, Amazon, is the second-biggest retailer globally, commanding nearly 40% of online retail sales in America. Since 2019, the number of Amazon employees has grown from 800,000 to over 1.5 million in 2023.

While the company has tried to introduce online grocery platforms to the market, it has largely fallen flat given its clunky system in a highly competitive market.

Like Amazon, China’s e-commerce juggernaut, Alibaba, stands as a leading global retailer. Overall, 97% of revenues were generated domestically through online marketplaces Taobao and Tmall. In recent years, the company has focused on international expansion, delivering products to 11 markets including America, in just five days.

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