The History of Psychedelics (Part 2 of 2)
In part one of this two-part series, we unearthed the story behind the prohibition of psychedelic substances, and how strict regulations resulted in a hugely stigmatized industry.
Over the last decade however, new breakthroughs proving the untapped therapeutic potential of medicinal psychedelics are coming to the fore, leading many to believe that restricting them may have in fact been premature.
The graphic above from Tryp Therapeutics is the last in a two part series that explores how psychedelics have evolved over the last 6,000 years.
The Psychedelic Renaissance
After decades of being labeled as illegal narcotics, the industry reinvented itself as a viable solution for treating hard-to-treat illnesses in a safe and controlled way.
“Psychedelics, used responsibly and with proper caution, would be for psychiatry what the microscope is for biology and medicine or the telescope is for astronomy.”
This unprecedented comeback has sparked a global medicinal psychedelics movement, with the U.S. leading the way in decriminalizing these powerful drugs.
|The FDA grants MDMA-assisted psychotherapy Breakthrough Therapy Status||U.S.|
|COMPASS Pathways receives Breakthrough Therapy Status from the FDA for a psilocybin synthetic derivative||U.S.|
|Esketamine is approved in the form of Spravato by the FDA, followed by European Commission approval||Global|
|Denver, Colorado and Oakland, California vote to decriminalize psilocybin mushrooms||U.S.|
|The world’s first microdosing study using LSD is approved in Auckland||New Zealand|
|Usona Institute receives Breakthrough Therapy Status for psilocybin treatment for Major Depression Disorder (MDD) ||U.S.|
|Santa Cruz, California votes to decriminalize psychedelic substances including psilocybin, ayahuasca, and peyote||U.S.|
|MindMed becomes the first publicly traded psychedelics company||U.S.|
|More than 45 companies claim to be engaged in the development and evaluation of therapeutic candidates from psychedelic substances||Global|
|Oregon legalizes psilocybin and decriminalizes all drugs||U.S|
|Washington, DC decriminalizes entheogenic psychedelics||U.S|
|New research suggests DMT can stimulate the production of new brain cells||Spain|
|MAPS completes first successful Phase III trial of MDMA-assisted psychotherapy||U.S.|
|Analysts announce that psychedelics could become a $100 billion market||Global|
With study after study proving the many benefits of utilizing psychedelic substances for a range of both mental and physical conditions, huge progress in legitimizing this once stigmatized industry is now being made.
The Future of Psychedelics
Psychedelics’ newfound momentum looks set to continue well into 2021 and beyond, with the first major milestones hinting at what the next decade could hold for the industry.
|2021 (Jan)||In Hawaii, a Senate bill put forward in January could legalize psilocybin and psilocin, otherwise known as magic mushrooms||U.S.
|2021 (Feb)||With California now introducing new legislation to decriminalize most psychedelic substances, we could see a sea-change of decriminalization across the world||U.S.|
|2021 (March)||Over 285 active, soon to be active, and completed psychedelics trials are recorded around the world ||Global|
The next chapter in the psychedelics story will center around biotechnology, new drug discoveries, and the many unknown applications of each of these substances.
Currently, the application of therapeutic psychedelics has mainly been targeted toward mental health conditions such as depression and anxiety. However, we have only scratched the surface when it comes to the myriad of ways we could harness the power of these sacred plants.
A New Era of Medicine
While the history of psychedelics is undoubtedly complex, it is clear that they are starting to play an important role in the evolution of medicine.
Even though studies on these substances were halted in the past, new research has proven the potential psychedelics have to alleviate some of the most hard-to-treat diseases when used in a safe, controlled environment.
As a result, these groundbreaking drugs could save millions of lives and add trillions of dollars to the global economy—and that’s just the beginning.
Tryp Therapeutics is an early leader in the psychedelic medicine space. The pharmaceutical company leverages the therapeutic properties of psilocybin to create new solutions for the treatment of diseases with high unmet medical needs.
7 Ways Artificial Intelligence is Improving Healthcare
Aritifical Intelligence becoming increasingly more prevalent in healthcare. Here are 7 ways this growth might impact the industry as a whole.
7 Ways Artificial Intelligence is Improving Healthcare
Emerging technologies have the potential to completely reshape the healthcare industry and the way people manage their health. In fact, tech innovation in healthcare and the use of artificial intelligence (AI) could provide more convenient, personalized care for patients.
It could also create substantially more value for the industry as a whole—up to $410 billion per year by 2025.
This graphic by RYAH MedTech explores the ways that technology, and more specifically AI, is transforming healthcare.
How is Technology Disrupting the Patient Experience?
Tech innovation is emerging across a wide range of medical applications.
Because of this, AI has the potential to impact every step of a patient’s journey—from early detection, to rehabilitation, and even follow-up appointments.
Here’s a look at each step in the patient journey, and how AI is expected to transform it:
Wearables and apps track vast amounts of personal data, so in the future, AI could use that information to make health recommendations for patients. For example, AI could track the glucose levels of patients with diabetes to provide personalized, real-time health advice.
2. Early Detection
Devices like smartwatches, biosensors, and fitness trackers can monitor things like heart rate and respiratory patterns. Because of this, health apps could notify users of any abnormalities before conditions become critical.
Wearables could also have a huge impact on fall prevention among seniors. AI-enabled accelerometer bracelets and smart belts could detect early warning signs, such as low grip strength, hydration levels, and muscle mass.
3. Doctors Visits
A variety of smart devices have the potential to provide support for healthcare workers. For instance, voice technology could help transcribe clinical data, which would mean less administrative work for healthcare workers, giving them more time to focus on patient care.
Virtual assistants are expected to take off in the next decade. In fact, the healthcare virtual assistant market is projected to reach USD $2.8 billion by 2027, at a CAGR of 27%.
4. Test Results
Traditionally, test results are analyzed manually, but AI has the potential to automate this process through pattern recognition. This would have a significant impact on infection testing.
5. Surgery / Hospital Visits
Research indicates that the use of robotics in surgery can save lives. In fact, one study found that robot assisted kidney surgeries saw a 52% increase in success rate.
Robotics can also support healthcare workers with repetitive tasks, such as restocking supplies, disinfecting patient rooms, and transporting medical equipment, which gives healthcare workers more time with their patients.
Personalized apps have significant care management potential. On the patient level, AI-enabled apps could be specifically tailored to individuals to track progress or adjust treatment plans based on real-time patient feedback.
On an industry level, data generated from users may have the potential to reduce costs on research and development, and improve the accuracy of clinical trials.
7. Follow-ups and Remote Monitoring
Virtual nurse apps can help patients stay accountable by consistently monitoring their own progress. This empowers patients by putting the control in their own hands.
This shift in power is already happening—for instance, a recent survey by Deloitte found that more than a third of respondents are willing to use at-home diagnostics, and more than half are comfortable telling their doctor when they disagree with them.
It’s All About the Experience
Through the use of wearables, smart devices, and personalized apps, patients are becoming increasingly more connected, and therefore less dependent on traditional healthcare.
However, as virtual care becomes more common, healthcare workers need to maintain a high quality of care. To do this, virtual training for physicians is critical, along with user-friendly platforms and intentionally designed apps to provide a seamless user experience.
Antimony: A Mineral with a Critical Role in the Green Future
Despite its lack of fanfare, antimony is a critical mineral that plays an important role in the mass storage of renewable energy.
Antimony: A Mineral with a Critical Role in the Green Future
If someone asked you to name the first mineral that came to mind, odds are, it wouldn’t be antimony.
Yet, despite its lack of fanfare, it plays a significant role in our day-to-day lives. This graphic from Perpetua Resources provides an overview of antimony’s key uses, and the critical role it plays in the movement towards clean energy, among other uses.
What even is Antimony?
Antimony is an element found in the earth’s crust. Rarely found in its native metallic form, it is primarily extracted from the sulfide mineral stibnite.
It has a variety of uses and is found in everything from household items to military-grade equipment. Because it conducts heat poorly, it’s used as a flame retardant in industrial uniforms, equipment, and even children’s clothing.
|End Use||% of antimony consumption in the U.S.|
|Transportation and batteries||29%|
|Ceramics and glass||12%|
Its second most common use, according to USGS, is in transportation and batteries. Traditionally, antimony has been combined with lead to create a strong, corrosion-resistant metal alloy, which is particularly useful in lead-acid batteries.
However, recent innovation has found a new use for antimony—it now plays an essential role in large-scale renewable energy storage, which is critical to the clean energy movement.
Antimony’s Role in Clean Energy
Large-scale renewable energy storage has been a massive hurdle for the clean energy transition because it’s hard to consistently generate renewable power. For instance, wind and solar farms might have a surplus of energy on windy or sunny days, but can fall short when the weather isn’t sunny, or when the wind stops.
Because of this, mass storage of renewable energy is key, in order to transition from fossil fuels to clean energy. Recent research points to liquid metal batteries as a potential storage solution—and these batteries heavily rely on antimony.
But there’s a finite supply, and with China currently dominating antimony production and processing, the U.S. could be at the mercy of its economic rival.
|Country||Production in 2020 (tons)||Reserves (tons)|
In 2020, there was no domestically mined production of antimony in America—meaning the U.S. relied on other countries, primarily China, for its antimony supply.
In the past, China has imposed restrictions on the exports of antimony-based products to the U.S., which reduced availability and increased prices. Because of this, antimony was identified as one of the 35 minerals that are critical to U.S. national security.
Tapping into Domestic Supply
To decrease foreign dependence, the U.S. could tap into domestic resources of antimony and build up its local supply chain.
The only major antimony deposit in North America is located in the Stibnite-Yellow Pine Mining District of central Idaho. This site is the largest reserve in the nation and is expected to supply roughly 35% of U.S. antimony demand on average for the first six years of production.
Domestic production would not only allow the U.S. to reduce its import reliance, but it would also create jobs, providing economic support for the local community.
In the near future, antimony demand could soar as a result of its critical role in clean energy storage—and domestic production via the Stibnite-Yellow Pine Mining district could play a key role in meeting this rising demand.
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