The History of Psychedelics (Part 2 of 2)
In part one of this two-part series, we unearthed the story behind the prohibition of psychedelic substances, and how strict regulations resulted in a hugely stigmatized industry.
Over the last decade however, new breakthroughs proving the untapped therapeutic potential of medicinal psychedelics are coming to the fore, leading many to believe that restricting them may have in fact been premature.
The graphic above from Tryp Therapeutics is the last in a two part series that explores how psychedelics have evolved over the last 6,000 years.
The Psychedelic Renaissance
After decades of being labeled as illegal narcotics, the industry reinvented itself as a viable solution for treating hard-to-treat illnesses in a safe and controlled way.
“Psychedelics, used responsibly and with proper caution, would be for psychiatry what the microscope is for biology and medicine or the telescope is for astronomy.”
This unprecedented comeback has sparked a global medicinal psychedelics movement, with the U.S. leading the way in decriminalizing these powerful drugs.
|The FDA grants MDMA-assisted psychotherapy Breakthrough Therapy Status||U.S.|
|COMPASS Pathways receives Breakthrough Therapy Status from the FDA for a psilocybin synthetic derivative||U.S.|
|Esketamine is approved in the form of Spravato by the FDA, followed by European Commission approval||Global|
|Denver, Colorado and Oakland, California vote to decriminalize psilocybin mushrooms||U.S.|
|The world’s first microdosing study using LSD is approved in Auckland||New Zealand|
|Usona Institute receives Breakthrough Therapy Status for psilocybin treatment for Major Depression Disorder (MDD) ||U.S.|
|Santa Cruz, California votes to decriminalize psychedelic substances including psilocybin, ayahuasca, and peyote||U.S.|
|MindMed becomes the first publicly traded psychedelics company||U.S.|
|More than 45 companies claim to be engaged in the development and evaluation of therapeutic candidates from psychedelic substances||Global|
|Oregon legalizes psilocybin and decriminalizes all drugs||U.S|
|Washington, DC decriminalizes entheogenic psychedelics||U.S|
|New research suggests DMT can stimulate the production of new brain cells||Spain|
|MAPS completes first successful Phase III trial of MDMA-assisted psychotherapy||U.S.|
|Analysts announce that psychedelics could become a $100 billion market||Global|
With study after study proving the many benefits of utilizing psychedelic substances for a range of both mental and physical conditions, huge progress in legitimizing this once stigmatized industry is now being made.
The Future of Psychedelics
Psychedelics’ newfound momentum looks set to continue well into 2021 and beyond, with the first major milestones hinting at what the next decade could hold for the industry.
|2021 (Jan)||In Hawaii, a Senate bill put forward in January could legalize psilocybin and psilocin, otherwise known as magic mushrooms||U.S.
|2021 (Feb)||With California now introducing new legislation to decriminalize most psychedelic substances, we could see a sea-change of decriminalization across the world||U.S.|
|2021 (March)||Over 285 active, soon to be active, and completed psychedelics trials are recorded around the world ||Global|
The next chapter in the psychedelics story will center around biotechnology, new drug discoveries, and the many unknown applications of each of these substances.
Currently, the application of therapeutic psychedelics has mainly been targeted toward mental health conditions such as depression and anxiety. However, we have only scratched the surface when it comes to the myriad of ways we could harness the power of these sacred plants.
A New Era of Medicine
While the history of psychedelics is undoubtedly complex, it is clear that they are starting to play an important role in the evolution of medicine.
Even though studies on these substances were halted in the past, new research has proven the potential psychedelics have to alleviate some of the most hard-to-treat diseases when used in a safe, controlled environment.
As a result, these groundbreaking drugs could save millions of lives and add trillions of dollars to the global economy—and that’s just the beginning.
Tryp Therapeutics is an early leader in the psychedelic medicine space. The pharmaceutical company leverages the therapeutic properties of psilocybin to create new solutions for the treatment of diseases with high unmet medical needs.
Every Cannabis Product In One Graphic
The cannabis industry is growing by billions every year. This graphic provides an overview of cannabis products and ranks their popularity.
Every Cannabis Product In One Graphic
There are few markets experiencing growth quite like cannabis, which in 2020 had an additional 7,000 products hit dispensary shelves compared to the year prior. However, for novice cannabis consumers and investors, the different products and their uses can be overwhelming.
This sponsored graphic by Tenacious Labs provides an overview of cannabis products, and is part of a multi-part series that covers different factors affecting the future of cannabis.
Let’s break down cannabis products on the market today.
First, is cannabis flower, which is the ingestible part of the cannabis plant and is the most popular way to consume. It is cultivated, harvested, dried, and cured, as part of the preparation process before making its way to the end consumer. Due to its popularity, it also represents the largest component of the U.S. legal market.
In 2021, some $10.9 billion in dried herb or “buds” were purchased. In addition, pre-rolls generated $2.2 billion, which are pre-rolled products prepared by dispensaries. The psychoactive effects from consuming flower are felt almost instantly, which remains a key appeal.
2. Cartridges, Concentrates, and Extracts
Cannabis concentrates are a growing category which have taken the market by storm in recent years. They come in various forms including raw concentrates, cartridges, and extracts. Preparing them involves removing impurities form the plant, leaving only the desired compounds such as cannabinoids and terpenes.
This highly concentrated form of cannabis results in THC levels of 80-90%, compared to the 10-20% range most commonly found in dry herb flower. Raw concentrates hit $2.2 billion in U.S. legal sales in 2021. And cartridges, which are products intended to be vaped and are typically paired with a battery accessory, were worth $5.1 billion.
The appeals associated with concentrates include a higher dose which results in stronger effects, plus a more discrete experience given they have little to no smell.
Next, are edibles, where the THC is metabolized by the liver and consumed through infused food and drinks. This leads to an different experience relative to inhaling. For example, the euphoric or psychoactive effects typically last much longer and can take 1-2 hours to kick in.
The legal U.S. edibles market is growing fast. It recorded revenues of $2.3 billion in 2021 but is expected to reach a value of $8.5 billion by 2027. These growth prospects have not gone unnoticed, in fact, the alcohol industry is betting big on cannabis. As of late, waves of investments and acquisitions are occurring targeting cannabis-infused beverages.
A key driver of growth comes from the health conscious consumer who may want to avoid the smoking process altogether.
4. Topicals and Others
Last are topicals and other products. Topicals are CBD-infused non-psychoactive products like lotions, balms, and oils. These are gaining notoriety for their wellness properties including the relief of pain, soreness, and inflammation. However, the market remains relatively modest, with a market value of $200 million. Furthermore, the topicals market appeals to those not interested in any psychoactive effects, and is particularly popular amongst women and pet owners.
Other products include papers, pipes, batteries, and all other accessories, which also provide notable revenues and opportunities.
Measuring Market Share of Cannabis Products
With all these products in mind, let’s take a look at market share. Although edibles, vapes, and concentrates have risen tremendously in value over the years, flower still remains number one, representing 43% of legal sales, followed by cartridges at 20.3% market share.
|Product||Market Share (%)||Market Value ($B)|
Seasonality also plays a role in cannabis consumption. Since dry flower tends to be consumed outdoors, the data shows that it loses market share during the cold winter months.
The Next Chapter
Cannabis products have come a long way from their early days when variety was considered a choice between an indica or sativa strain. As the industry develops and more money is injected into the space, we should see product innovation accelerate even further.
Visualizing the Evolution of the Global Meat Market
The global meat market will be worth $1.8 trillion by 2040, but how much of that will plant-based alternatives and cultured meat command?
The Evolution of the Global Meat Market
In the last decade, there has been an undeniable shift in consumers’ preferences when it comes to eating meat.
This is partly due to the wide availability of meat replacement options combined with growing awareness of their health benefits and lower impact on the environment compared to conventional meat.
In this infographic from CULT Food Science (CSE: CULT), we examine how meat consumption is expected to evolve over the next two decades. Let’s dive in.
Taking a Bite out of Meat’s Market Share
The COVID-19 pandemic triggered a massive turning point for the meat industry, and it will continue to evolve dramatically over the next 20 years. Taking inflation into account, the global meat market is expected to grow overall by roughly 3% by 2040 as a result of population growth.
However, as consumption shifts, conventional meat supply is expected to decline by more than 33% according to Kearney. These products will be replaced by innovative meat alternatives, some of which have yet to hit the mass market.
- Novel vegan meat replacement: These are meat alternatives products made from plants that resemble the taste and texture of meat.
- Cultured meat: Also referred to as clean, cultivated, or lab grown meats, cultured meat is a genuine meat product that is produced by cultivating animal cells in a controlled environment without the need to harm animals.
Aside from new meat replacements, biotech will also transform adjacent industries like dairy, eggs, and fish.
The Future of Food?
Meat replacements and cultured meat could overtake the conventional meat market, with cultured meats reigning supreme overall with a 41% annual growth rate (CAGR) between 2025 and 2040.
New technologies for cultivating non-animal based protein will provide one-third of the global meat supply due to an increase in commercial competitiveness and consumers becoming more accepting of these kinds of products.
Meanwhile, conventional meat will make up just 40% of all global meat supply by 2040, compared to 90% in 2025. For this very reason, conventional meat producers are investing a significant amount of capital in meat alternative companies so they can avoid disruption.
Invest in the Revolution
The changing tides in the industry have sparked a variety of undeniable opportunities:
- Regulatory approvals: Singapore is the first country to legalize cultured meat for consumers, and many more will no doubt follow behind in the coming years.
- Lower production costs: Cultured meat and dairy have made quantum leaps in reducing production costs.
- Changing consumer ethics: Consumers are demanding a more ethical approach to factory farming and cultured and plant-based alternative products are becoming a more accepted solution.
CULT Food Science (CSE: CULT) is a cutting edge investment platform advancing the future of food. The first-of-its-kind in North America, CULT aims to provide unprecedented exposure to the most innovative start-up, private or early stage lab grown food companies around the world.
Will you be part of the revolution?
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