The 50 Most Important Life-Saving Breakthroughs in History
For most of civilized history, life expectancy fluctuated in the 30 to 40 year range.
Child mortality was all too common, and even for those that made it to adulthood, a long and healthy life was anything but guaranteed. Sanitation was poor, disease was rampant, and many medical practices were based primarily on superstition or guesswork.
By the 20th century, an explosion in new technologies, treatments, and other science-backed practices helped to increase global life expectancy at an unprecedented rate.
From 1900 to 2015, global life expectancy more than doubled, shooting well past the 70 year mark.
What were the major innovations that made the last century so very fruitful in saving lives?
Today’s infographic from AperionCare highlights the top 50 breakthroughs, ranging from pasteurization to the bifurcated needle, that have helped propel global life expectancy upwards.
Interestingly, while many of these innovations have some linkage to the medical realm, there are also breakthroughs in sectors like energy, sanitation, and agriculture that have helped us lead longer and healthier lives.
To see innovations on an individual basis, AperionCare breaks them down further as follows:
The breakthroughs that are credited with saving the most lives?
Toilets, synthetic fertilizers, blood transfusions, the green revolution (also known as the “Third Agricultural Revolution”), and vaccines are each credited with saving 1 billion lives. Meanwhile, pasteurization, water chlorination, antibiotics, antimalarial drugs, and the bifurcated needle have saved hundreds of millions of lives each.
There are also some unusual entries to the list.
It turns out that satellites have actually saved 250,000 lives, thanks to the ability to better forecast natural disasters. Nuclear power also gets a shout out – and it may surprise some people that nuclear energy is the least deadly form of energy per kilowatt generated.
Progress in Life Expectancy
For a graphical look at how this all has impacted life expectancy, the following chart from Our World in Data makes a very clear case:
The impact from these new technologies was first experienced in Europe at the end of the 1800s – and other continents quickly saw the benefits thereafter.
Impressively, Africa has now passed the 60 year mark in life expectancy, with numbers still rising.
How the Top Cryptocurrencies Performed in 2021
Cryptocurrencies had a breakout year in 2021, providing plenty of volatility and strong returns across crypto’s various sectors.
The Returns of Top Cryptocurrencies in 2021
2021 saw the crypto markets boom and mature, with different sectors flourishing and largely outperforming the market leader, bitcoin.
While bitcoin only managed to return 59.8% last year, the crypto sector’s total market cap grew by 187.5%, with many of the top coins offering four and even five-digit percentage returns.
2021 Crypto Market Roundup
Last year wasn’t just a breakout year for crypto in terms of returns, but also the growing infrastructure’s maturity and resulting decorrelation of individual crypto industries and coins.
Crypto’s infrastructure has developed significantly, and there are now many more onramps for people to buy altcoins that don’t require purchasing and using bitcoin in the process. As a result, many cryptocurrency prices were more dictated by the value and functionality of their protocol and applications rather than their correlation to bitcoin.
|Ethereum||Smart Contract Platform||399.2%|
|Binance Coin||Exchange Token||1,268.9%|
|Solana||Smart Contract Platform||11,177.8%|
|Cardano||Smart Contract Platform||621.3%|
|Terra||Smart Contract Platform||12,967.3%|
|Avalanche||Smart Contract Platform||3,334.8%|
|Polkadot||Smart Contract Platform||187.9%|
Sources: TradingView, Binance, Uniswap, FTX, Bittrex
Bitcoin wasn’t the only cryptocurrency that didn’t manage to reach triple-digit returns in 2021. Litecoin and Bitcoin Cash also provided meagre double-digit percentage returns, as payment-focused cryptocurrencies were largely ignored for projects with smart contract capabilities.
Other older projects like Stellar Lumens (109%) and XRP (278%) provided triple-digit returns, with Cardano (621%) being the best performer of the old guard despite not managing to ship its smart contract functionality last year.
The Rise of the Ethereum Competitors
Ethereum greatly outpaced bitcoin in 2021, returning 399.2% as the popularity boom of NFTs and creation of DeFi 2.0 protocols like Olympus (OHM) expanded possible use-cases.
But with the rise of network activity, a 50% increase in transfers in 2021, Ethereum gas fees surged. From minimums of $20 for a single transaction, to NFT mint prices starting around $40 and going into the hundreds on congested network days, crypto’s retail crowd migrated to other smart contract platforms with lower fees.
Alternative budding smart contract platforms like Solana (11,178%), Avalanche (3,335%), and Fantom (13,207%) all had 4-5 digit percentage returns, as these protocols built out their own decentralized finance ecosystems and NFT markets.
With Ethereum set to merge onto the beacon chain this year, which uses proof of stake instead of proof of work, we’ll see if 2022 brings lower gas fees and retail’s return to Ethereum if the merge is successful.
Dog Coins Meme their Way to the Top
While many new cryptocurrencies with strong functionality and unique use-cases were rewarded with strong returns, it was memes that powered the greatest returns in cryptocurrencies this past year.
Dogecoin’s surge after Elon Musk’s “adoption” saw many other dog coins follow, with SHIB benefitting the most and returning an astounding 19.85 million percent.
But ever since Dogecoin’s run from $0.07 to a high of $0.74 in Q2 of last year, the original meme coin’s price has slowly bled -77% down to $0.17 at the time of writing. After the roller coaster ride of last year, 2022 started with a positive catalyst for Dogecoin holders as Elon Musk announced DOGE can be used to purchase Tesla merchandise.
Gamifying the Crypto Industry
The intersection between crypto, games, and the metaverse became more than just a pipe dream in 2021. Axie Infinity was the first crypto native game to successfully establish a play to earn structure that combines its native token (AXS) and in-game NFTs, becoming a sensation and source of income for many in the Philippines.
Other crypto gaming projects like Defi Kingdoms are putting recognizable game interfaces on decentralized finance applications, with the decentralized exchange becoming the town’s “marketplace” and yield farms being the “gardens” where yield is harvested. This fantasy aesthetic is more than just a new coat of paint, as the project with $1.04B of total value locked is developing an underlying play-to-earn game.
Along with gamification, 2021 saw crypto native and non-crypto developers put a big emphasis on the digital worlds or metaverses users will inhabit. Facebook’s name change to Meta resulted in the two prominent metaverse projects The Sandbox (SAND) and Decentraland (MANA) surge another few hundred percent to finish off the year at 16,261% and 4,104% returns respectively.
With so many eyes on the crypto sector after the 2021’s breakout year, we’ll see how developing U.S. regulation and changing macro conditions affect cryptocurrencies in 2022.
The 20 Internet Giants That Rule the Web
A lot has changed since Yahoo and AOL were the homepages of choice. This visualization looks at the largest internet giants in the U.S. since 1998.
The 20 Internet Giants That Rule the Web (1998-Today)
With each passing year, an increasingly large segment of the population no longer remembers images loading a single pixel row at a time, the earsplitting sound of a 56k modem, or the early domination of web portals.
Many of the top websites in 1998 were news aggregators or search portals, which are easy concepts to understand. Today, brand touch-points are often spread out between devices (e.g. mobile apps vs. desktop) and a myriad of services and sub-brands (e.g. Facebook’s constellation of apps). As a result, the world’s biggest websites are complex, interconnected web properties.
The visualization above, which primarily uses data from ComScore’s U.S. Multi-Platform Properties ranking, looks at which of the internet giants have evolved to stay on top, and which have faded into internet lore.
America Moves Online
For millions of curious people the late ’90s, the iconic AOL compact disc was the key that opened the door to the World Wide Web. At its peak, an estimated 35 million people accessed the internet using AOL, and the company rode the Dotcom bubble to dizzying heights, reaching a valuation of $222 billion dollars in 1999.
AOL’s brand may not carry the caché it once did, but the brand never completely faded into obscurity. The company continually evolved, finally merging with Yahoo after Verizon acquired both of the legendary online brands. Verizon had high hopes for the company—called Oath—to evolve into a “third option” for advertisers and users who were fed up with Google and Facebook.
Sadly, those ambitions did not materialize as planned. In 2019, Oath was renamed Verizon Media, and was eventually sold once again in 2021.
A City of Gifs and Web Logs
As internet usage began to reach critical mass, web hosts such as AngelFire and GeoCities made it easy for people to create a new home on the Web.
GeoCities, in particular, made a huge impact on the early internet, hosting millions of websites and giving people a way to actually participate in creating online content. If it were a physical community of “home” pages, it would’ve been the third largest city in America, after Los Angeles.
This early online community was at risk of being erased permanently when GeoCities was finally shuttered by Yahoo in 2009, but luckily, the nonprofit Internet Archive took special efforts to create a thorough record of GeoCities-hosted pages.
From A to Z
In December of 1998, long before Amazon became the well-oiled retail machine we know today, the company was in the midst of a massive holiday season crunch.
In the real world, employees were pulling long hours and even sleeping in cars to keep the goods flowing, while online, Amazon.com had become one of the biggest sites on the internet as people began to get comfortable with the idea of purchasing goods online. Demand surged as the company began to expand their offering beyond books.
Amazon.com has grown to be the most successful merchant on the Internet.
– New York Times (1998)
Digital Magazine Rack
Meredith will be an unfamiliar brand to many people looking at today’s top 20 list. While Meredith may not be a household name, the company controlled many of the country’s most popular magazine brands (People, AllRecipes, Martha Stewart, Health, etc.) including their sizable digital footprints. The company also owned a slew of local television networks around the United States.
After its acquisition of Time Inc. in 2017, Meredith became the largest magazine publisher in the world. Since then, however, Meredith has divested many of its most valuable assets (Time, Sports Illustrated, Fortune). In December 2021, Meredith merged with IAC’s Dotdash.
When people have burning questions, they increasingly turn to the internet for answers, but the diversity of sources for those answers is shrinking.
Even as recently as 2013, we can see that About.com, Ask.com, and Answers.com were still among the biggest websites in America. Today though, Google appears to have cemented its status as a universal wellspring of answers.
As smart speakers and voice assistants continue penetrate the market and influence search behavior, Google is unlikely to face any near-term competition from any company not already in the top 20 list.
New Kids on the Block
Social media has long since outgrown its fad stage and is now a common digital thread connecting people across the world. While Facebook rapidly jumped into the top 20 by 2007, other social media infused brands took longer to grow into internet giants.
By 2018, Twitter, Snapchat, and Facebook’s umbrella of platforms were all in the top 20, and you can see a more detailed and up-to-date breakdown of the social media universe here.
A Tangled Web
Today’s internet giants have evolved far beyond their ancestors from two decades ago. Many of the companies in the top 20 run numerous platforms and content streams, and more often than not, they are not household names.
A few, such as Mediavine and CafeMedia, are services that manage ads. Others manage content distribution, such as music, or manage a constellation of smaller media properties, as is the case with Hearst.
Lastly, there are still the tech giants. Remarkably, three of the top five web properties were in the top 20 list in 1998. In the fast-paced digital ecosystem, that’s some remarkable staying power.
This article was inspired by an earlier work by Philip Bump, published in the Washington Post.
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