Healthcare
The 50 Most Important Life-Saving Breakthroughs in History
The 50 Most Important Life-Saving Breakthroughs in History
For most of civilized history, life expectancy fluctuated in the 30 to 40 year range.
Child mortality was all too common, and even for those that made it to adulthood, a long and healthy life was anything but guaranteed. Sanitation was poor, disease was rampant, and many medical practices were based primarily on superstition or guesswork.
By the 20th century, an explosion in new technologies, treatments, and other science-backed practices helped to increase global life expectancy at an unprecedented rate.
From 1900 to 2015, global life expectancy more than doubled, shooting well past the 70 year mark.
Important Breakthroughs
What were the major innovations that made the last century so very fruitful in saving lives?
Today’s infographic from AperionCare highlights the top 50 breakthroughs, ranging from pasteurization to the bifurcated needle, that have helped propel global life expectancy upwards.
Interestingly, while many of these innovations have some linkage to the medical realm, there are also breakthroughs in sectors like energy, sanitation, and agriculture that have helped us lead longer and healthier lives.
To see innovations on an individual basis, AperionCare breaks them down further as follows:
The breakthroughs that are credited with saving the most lives?
Toilets, synthetic fertilizers, blood transfusions, the green revolution (also known as the “Third Agricultural Revolution”), and vaccines are each credited with saving 1 billion lives. Meanwhile, pasteurization, water chlorination, antibiotics, antimalarial drugs, and the bifurcated needle have saved hundreds of millions of lives each.
There are also some unusual entries to the list.
It turns out that satellites have actually saved 250,000 lives, thanks to the ability to better forecast natural disasters. Nuclear power also gets a shout out – and it may surprise some people that nuclear energy is the least deadly form of energy per kilowatt generated.
Progress in Life Expectancy
For a graphical look at how this all has impacted life expectancy, the following chart from Our World in Data makes a very clear case:
The impact from these new technologies was first experienced in Europe at the end of the 1800s – and other continents quickly saw the benefits thereafter.
Impressively, Africa has now passed the 60 year mark in life expectancy, with numbers still rising.
Healthcare
Visualized: The Global Syringe Shortage Threatening Vaccine Efforts
A backlog of routine and COVID-19 vaccinations has led to skyrocketing demand for syringes. What role will needle-free devices play?


The Global Syringe Shortage Threatening Vaccine Efforts
Routine vaccination saves millions of lives every single year, according to the World Health Organization (WHO).
But even though global vaccination coverage is improving, closing the gap in immunization has led to skyrocketing demand for syringes—which is forecast to result in a major shortage that could make matters worse.
In the above infographic from NuGen Medical Devices, we explore the factors leading to the syringe shortage and take a look at the company’s innovative needle-free solution that could play an important role in closing the immunization gap.
The Immunization Gap
Even before the COVID-19 pandemic, millions of people around the world struggled to get access to routine vaccinations.
In fact, as of 2019 more than 19 million children around the world were considered to be “zero-dose” which means that they did not receive any routine vaccinations.
Moreover, when the COVID-19 pandemic hit, global immunization dropped even further with 25 million children missing out on routine vaccines in 2021 alone.
Why is Immunization So Important?
Vaccinations prevent against over 20 life-threatening diseases and save between 2-3 million deaths per year, making them—as the WHO describes—the foundation of healthcare systems and an indisputable human right.

As countries work through a backlog of vaccinations to close the immunization gap that has worsened since the pandemic, demand for syringes has significantly increased.
The Result: A Global Syringe Deficit
In 2022, the WHO warned that we could see a shortage of up to 2 billion syringes if manufacturing can’t keep up. This could result in the severe disruption to routine vaccinations and promote unsafe recycling of syringes in order to administer vaccines.
But the issue goes far beyond a supply shortage of syringes. COVID-19 has brought conventional syringe vaccines into sharp focus, with many criticizing the challenges associated with them.
The Challenge | |||
Vaccine Hesitancy: 1 in 10 Americans have an extreme fear of needles and therefore will avoid vaccination. | Affordability: The cost of essential syringe vaccination makes them inaccessible for people living in low and middle income countries. | Cost of Logistics: Geographical constrains, a lack of infrastructure, and the need to keep vaccines at sub-zero temperatures prevent them from reaching those who need it the most. | Biohazardous Waste: 7.8 billion needles are discarded in the U.S. every year. |
The Solution | |||
Reduce Fear: Needle-free devices remove the fear of syringes. | Reduce Costs: Needle-free devices are lower in cost per injection compared to conventional needles. | Minimizes Cold Chain: NuGen MD’s next generation powder injectables minimize the need for a cold chain (keeping vaccines at sub-zero temperatures) entirely. | Sustainable Needles: Needle-free technology reduces environmental waste significantly. |
With conventional needles facing so many challenges, it’s no surprise that investors are taking interest in viable alternatives. What’s more, these alternatives don’t just apply to vaccinations, they can also work for people with diabetes, dentists, and pet care.
Enter Needle-free Devices from NuGen MD
Needle-free devices have the potential to bridge the gap in immunization amid the global syringe shortage, solve some of the key challenges limiting vaccine uptake, and more importantly, benefit the lives of millions of people.
How Do They Work?
NuGen’s needle-free devices use a simple spring-loaded mechanism which uses pressure to release the liquid drug and penetrate the skin. In less than one-tenth of a second, the drug is dispensed more safely and evenly compared to needle syringes. It’s also virtually painless and leaves no mark on the skin.
>>>Interested in investing in NuGen Medical Devices? To learn more about their plans to pioneer the future of needle-free drug delivery, click this link now.

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